Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 5055007..5055744 Replicon chromosome
Accession NZ_LR882967
Organism Planktothrix pseudagardhii strain No.713

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag NMK36_RS21815 Protein ID WP_254174602.1
Coordinates 5055007..5055267 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag NMK36_RS21820 Protein ID WP_254174603.1
Coordinates 5055406..5055744 (+) Length 113 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMK36_RS21800 (NO713_04367) 5050879..5052771 + 1893 WP_254174600.1 hypothetical protein -
NMK36_RS21805 (NO713_04368) 5052768..5053880 - 1113 WP_254172743.1 IS630 family transposase -
NMK36_RS21810 (NO713_04369) 5054084..5054863 + 780 WP_254174601.1 hypothetical protein -
NMK36_RS21815 (NO713_04370) 5055007..5055267 + 261 WP_254174602.1 type II toxin-antitoxin system HicA family toxin Toxin
NMK36_RS21820 (NO713_04371) 5055406..5055744 + 339 WP_254174603.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
NMK36_RS21825 (NO713_04372) 5056526..5056777 + 252 WP_254174604.1 DUF2281 domain-containing protein -
NMK36_RS21830 (NO713_04373) 5056781..5057203 + 423 WP_254174605.1 PIN domain-containing protein -
NMK36_RS21835 (NO713_04374) 5057267..5059927 - 2661 WP_254174606.1 EAL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(25-83)

Antitoxin

Uncharacterised protein family HicB

(52-102)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9835.42 Da        Isoelectric Point: 11.5333

>T289996 WP_254174602.1 NZ_LR882967:5055007-5055267 [Planktothrix pseudagardhii]
MSLNNKQRRTLELIFTDPIPTTINWQDIENLFQALGATIMQGRGSRIRVLLNNVRAIFHQPHPQKETDRGAVKSVREFLI
KAGVKP

Download         Length: 261 bp

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12828.57 Da        Isoelectric Point: 4.7370

>AT289996 WP_254174603.1 NZ_LR882967:5055406-5055744 [Planktothrix pseudagardhii]
MLNYKGYTAQIEVDVEAGILFGQVLDINDVITFKGKTVEEIRQEFKNSIDDYLEFCQELGQEPDKPFSGKLPFRTTPENH
RKIFLAAKKAGKSINAWMDETLIREANQTIQT

Download         Length: 339 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References