Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3614378..3614972 Replicon chromosome
Accession NZ_LR882967
Organism Planktothrix pseudagardhii strain No.713

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NMK36_RS15275 Protein ID WP_254174098.1
Coordinates 3614378..3614737 (-) Length 120 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NMK36_RS15280 Protein ID WP_072719471.1
Coordinates 3614727..3614972 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMK36_RS15245 (NO713_03050) 3609486..3609719 - 234 WP_072719380.1 2Fe-2S iron-sulfur cluster-binding protein -
NMK36_RS15250 (NO713_03051) 3609744..3611207 - 1464 WP_254174097.1 cobyric acid synthase CobQ -
NMK36_RS15255 (NO713_03052) 3611320..3611991 + 672 WP_072719378.1 uracil phosphoribosyltransferase -
NMK36_RS15260 (NO713_03053) 3612107..3612403 + 297 WP_072719377.1 hypothetical protein -
NMK36_RS15265 (NO713_03054) 3612515..3612805 + 291 WP_072719376.1 YggT family protein -
NMK36_RS15270 (NO713_03055) 3612918..3614285 - 1368 WP_072719375.1 thioredoxin-disulfide reductase -
NMK36_RS15275 (NO713_03056) 3614378..3614737 - 360 WP_254174098.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NMK36_RS15280 (NO713_03057) 3614727..3614972 - 246 WP_072719471.1 hypothetical protein Antitoxin
NMK36_RS15285 (NO713_03058) 3615433..3616122 + 690 WP_254174099.1 class I SAM-dependent methyltransferase -
NMK36_RS15290 (NO713_03059) 3616155..3617189 + 1035 WP_072719372.1 aldo/keto reductase -
NMK36_RS15295 (NO713_03060) 3617232..3619004 - 1773 WP_254174100.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(33-106)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 120 a.a.        Molecular weight: 13631.73 Da        Isoelectric Point: 9.7524

>T289995 WP_254174098.1 NZ_LR882967:c3614737-3614378 [Planktothrix pseudagardhii]
MLSEPPPIQIALTPRFKRDLRELAKHYRSIRTDLQPLIEQLQAGEIPGDRIAGIKYTVFKVRLKNSNIQKGKSGGYRVIY
YLKTNQAIILATIYSKSDDSDISHKIIEEVITQYENEIG

Download         Length: 360 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8924.01 Da        Isoelectric Point: 3.7437

>AT289995 WP_072719471.1 NZ_LR882967:c3614972-3614727 [Planktothrix pseudagardhii]
MKAIETTATINESGQLTLDQSLGTTKPQRVRVIVLIPEDDEVDPNETPTEILIEGIRQGLYEALTGQTIPLSEMWEGIDA
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References