Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 3218762..3219339 Replicon chromosome
Accession NZ_LR882967
Organism Planktothrix pseudagardhii strain No.713

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag NMK36_RS13680 Protein ID WP_254173966.1
Coordinates 3218762..3219103 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID A0A1J1LPA2
Locus tag NMK36_RS13685 Protein ID WP_072720577.1
Coordinates 3219097..3219339 (-) Length 81 a.a.

Genomic Context

NMK36_RS13665NMK36_RS13670NMK36_RS13675NMK36_RS13700NMK36_RS13660NMK36_RS13680NMK36_RS13685NMK36_RS13690NMK36_RS13695NMK36_RS13705
Location: 3215307..3215912 (606 bp)
Type: Others
Protein ID: WP_190522800.1
Location: 3216001..3217329 (1329 bp)
Type: Others
Protein ID: WP_254173964.1
Location: 3217382..3218701 (1320 bp)
Type: Others
Protein ID: WP_254173965.1
Location: 3221757..3222044 (288 bp)
Type: Others
Protein ID: WP_139295122.1
Location: 3214695..3214964 (270 bp)
Type: Others
Protein ID: WP_072720572.1
Location: 3218762..3219103 (342 bp)
Type: Toxin
Protein ID: WP_254173966.1
Location: 3219097..3219339 (243 bp)
Type: Antitoxin
Protein ID: WP_072720577.1
Location: 3219545..3220468 (924 bp)
Type: Others
Protein ID: WP_072720578.1
Location: 3220635..3221660 (1026 bp)
Type: Others
Protein ID: WP_254173967.1
Location: 3222065..3223366 (1302 bp)
Type: Others
Protein ID: WP_254173968.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NMK36_RS13660 (NO713_02729)3214695..3214964-270WP_072720572.1hypothetical protein-
NMK36_RS13665 (NO713_02730)3215307..3215912+606WP_190522800.1NfeD-like protein-
NMK36_RS13670 (NO713_02731)3216001..3217329+1329WP_254173964.1SPFH domain-containing protein-
NMK36_RS13675 (NO713_02732)3217382..3218701+1320WP_254173965.1SPFH domain-containing protein-
NMK36_RS13680 (NO713_02733)3218762..3219103-342WP_254173966.1type II toxin-antitoxin system PemK/MazF family toxinToxin
NMK36_RS13685 (NO713_02734)3219097..3219339-243WP_072720577.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
NMK36_RS13690 (NO713_02735)3219545..3220468-924WP_072720578.1ornithine carbamoyltransferase-
NMK36_RS13695 (NO713_02736)3220635..3221660-1026WP_254173967.1tRNA dihydrouridine synthase DusB-
NMK36_RS13700 (NO713_02737)3221757..3222044+288WP_139295122.1hypothetical protein-
NMK36_RS13705 (NO713_02738)3222065..3223366-1302WP_254173968.1cyclic nucleotide-binding domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-111)

Antitoxin

Antitoxin PemI-like

(1-80)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12932.06 Da        Isoelectric Point: 6.2191

>T289994 WP_254173966.1 NZ_LR882967:c3219103-3218762 [Planktothrix pseudagardhii]
MVNQSYIPDRGHIVKLNFNPTQGHEQKGLRPAFVISPYEYNVKNSLALFMPITAQVKGYPFEVSLPSELTTYGVILVDHI
KSLDYKVRLIQFIEIVPEDVIQEVQAKIEVLIF

Download         Length: 342 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8769.86 Da        Isoelectric Point: 4.9313

>AT289994 WP_072720577.1 NZ_LR882967:c3219339-3219097 [Planktothrix pseudagardhii]
MVTNVAKWGNSLAVRIPQNIAQAIQISEGSQVTFSVENGTIVIKPSNRKRYSLEELVSQITPENCHTETDTGLAVGNEVW

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1J1LPA2

References