Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-DUF433
Location 2652062..2652804 Replicon chromosome
Accession NZ_LR882967
Organism Planktothrix pseudagardhii strain No.713

Toxin (Protein)


Gene name vapC Uniprot ID A0A1J1LQY8
Locus tag NMK36_RS11230 Protein ID WP_072721835.1
Coordinates 2652062..2652469 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1J1LSZ9
Locus tag NMK36_RS11235 Protein ID WP_072721833.1
Coordinates 2652571..2652804 (+) Length 78 a.a.

Genomic Context

NMK36_RS11225NMK36_RS11230NMK36_RS11235NMK36_RS11240NMK36_RS11255NMK36_RS11260NMK36_RS11265NMK36_RS11215NMK36_RS11220NMK36_RS11245NMK36_RS11250NMK36_RS11270NMK36_RS11275
Location: 2651863..2652075 (213 bp)
Type: Others
Protein ID: WP_072721837.1
Location: 2652062..2652469 (408 bp)
Type: Toxin
Protein ID: WP_072721835.1
Location: 2652571..2652804 (234 bp)
Type: Antitoxin
Protein ID: WP_072721833.1
Location: 2652801..2653142 (342 bp)
Type: Others
Protein ID: WP_254173733.1
Location: 2653910..2654434 (525 bp)
Type: Others
Protein ID: WP_254173735.1
Location: 2654783..2655016 (234 bp)
Type: Others
Protein ID: WP_254173736.1
Location: 2655072..2655482 (411 bp)
Type: Others
Protein ID: WP_072721824.1
Location: 2648500..2651139 (2640 bp)
Type: Others
Protein ID: WP_254173731.1
Location: 2651251..2651688 (438 bp)
Type: Others
Protein ID: WP_254173732.1
Location: 2653150..2653416 (267 bp)
Type: Others
Protein ID: WP_254173734.1
Location: 2653413..2653622 (210 bp)
Type: Others
Protein ID: WP_072721829.1
Location: 2655511..2655993 (483 bp)
Type: Others
Protein ID: WP_254173737.1
Location: 2656075..2656518 (444 bp)
Type: Others
Protein ID: WP_254173738.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NMK36_RS11215 (NO713_02233)2648500..2651139-2640WP_254173731.1C39 family peptidase-
NMK36_RS11220 (NO713_02234)2651251..2651688-438WP_254173732.1peroxiredoxin-
NMK36_RS11225 (NO713_02235)2651863..2652075+213WP_072721837.1type II toxin-antitoxin system VapB family antitoxin-
NMK36_RS11230 (NO713_02236)2652062..2652469+408WP_072721835.1PIN domain nucleaseToxin
NMK36_RS11235 (NO713_02237)2652571..2652804+234WP_072721833.1DUF433 domain-containing proteinAntitoxin
NMK36_RS11240 (NO713_02238)2652801..2653142+342WP_254173733.1DUF5615 family PIN-like protein-
NMK36_RS11245 (NO713_02239)2653150..2653416-267WP_254173734.1type II toxin-antitoxin system RelE/ParE family toxin-
NMK36_RS11250 (NO713_02240)2653413..2653622-210WP_072721829.1hypothetical protein-
NMK36_RS11255 (NO713_02241)2653910..2654434+525WP_254173735.1DUF262 domain-containing protein-
NMK36_RS11260 (NO713_02242)2654783..2655016+234WP_254173736.1hypothetical protein-
NMK36_RS11265 (NO713_02243)2655072..2655482+411WP_072721824.1hypothetical protein-
NMK36_RS11270 (NO713_02244)2655511..2655993-483WP_254173737.1DUF4168 domain-containing protein-
NMK36_RS11275 (NO713_02245)2656075..2656518-444WP_254173738.1DUF4168 domain-containing protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-120)

Antitoxin

Protein of unknown function DUF433

(11-66)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15892.06 Da        Isoelectric Point: 5.7402

>T289992 WP_072721835.1 NZ_LR882967:2652062-2652469 [Planktothrix pseudagardhii]
MFLIDTSVWISVFRDRTGAVRQSLEAIINNKSIFLSRFTQMELLQGCRDDREWTLLETYLQDQDYIEATADTWVAAARIY
YDLQRQGLTVRSSIDCCIAQLAIKHQLTLVHNDRDFETIQRVRSLNCLRFRPENN

Download         Length: 408 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8591.02 Da        Isoelectric Point: 4.6320

>AT289992 WP_072721833.1 NZ_LR882967:2652571-2652804 [Planktothrix pseudagardhii]
MNLTTGLLNRITQTPGQCGGRPCIRGMRIRVTDILEMLAENVSITEILEDFPDLELADIQACLLFAARRTDFPRLTA

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A1J1LQY8

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A1J1LSZ9

References