Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 2273217..2273830 Replicon chromosome
Accession NZ_LR882967
Organism Planktothrix pseudagardhii strain No.713

Toxin (Protein)


Gene name vapC Uniprot ID A0A7Z9BN42
Locus tag NMK36_RS09550 Protein ID WP_072722242.1
Coordinates 2273217..2273603 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A7Z9BU65
Locus tag NMK36_RS09555 Protein ID WP_072722241.1
Coordinates 2273600..2273830 (-) Length 77 a.a.

Genomic Context

NMK36_RS09540NMK36_RS09545NMK36_RS09560NMK36_RS09570NMK36_RS09575NMK36_RS09550NMK36_RS09555NMK36_RS09565
Location: 2268616..2269695 (1080 bp)
Type: Others
Protein ID: WP_072722243.1
Location: 2269932..2273015 (3084 bp)
Type: Others
Protein ID: WP_254173612.1
Location: 2274012..2275217 (1206 bp)
Type: Others
Protein ID: WP_072722240.1
Location: 2276063..2277496 (1434 bp)
Type: Others
Protein ID: WP_254173613.1
Location: 2277599..2278588 (990 bp)
Type: Others
Protein ID: WP_072722237.1
Location: 2273217..2273603 (387 bp)
Type: Toxin
Protein ID: WP_072722242.1
Location: 2273600..2273830 (231 bp)
Type: Antitoxin
Protein ID: WP_072722241.1
Location: 2275264..2275758 (495 bp)
Type: Others
Protein ID: WP_072722239.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NMK36_RS09540 (NO713_01905)2268616..2269695+1080WP_072722243.1fructose-bisphosphate aldolase class II-
NMK36_RS09545 (NO713_01906)2269932..2273015+3084WP_254173612.1N-6 DNA methylase-
NMK36_RS09550 (NO713_01907)2273217..2273603-387WP_072722242.1type II toxin-antitoxin system VapC family toxinToxin
NMK36_RS09555 (NO713_01908)2273600..2273830-231WP_072722241.1DUF2281 domain-containing proteinAntitoxin
NMK36_RS09560 (NO713_01909)2274012..2275217+1206WP_072722240.1sodium/glutamate symporter-
NMK36_RS09565 (NO713_01910)2275264..2275758-495WP_072722239.1hypothetical protein-
NMK36_RS09570 (NO713_01911)2276063..2277496+1434WP_254173613.1circularly permuted type 2 ATP-grasp protein-
NMK36_RS09575 (NO713_01912)2277599..2278588+990WP_072722237.1alpha-E domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

VapC-like Sll0205 protein, PIN domain

(5-127)

Antitoxin

Domain of unknown function DUF2281

(6-74)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14991.42 Da        Isoelectric Point: 4.6643

>T289991 WP_072722242.1 NZ_LR882967:c2273603-2273217 [Planktothrix pseudagardhii]
MNSFLLDTHTFIWLSENDPNLPDSLREMIDIADHVYLSIASLWEIAIKLNLGKLSLQQSYKTIEDKLENSDILLLPIMFI
DTLQICNLPLHHRDPFDRMLIAQAINRSLILISRDIKFDAYPIQRLWD

Download         Length: 387 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8911.16 Da        Isoelectric Point: 4.1813

>AT289991 WP_072722241.1 NZ_LR882967:c2273830-2273600 [Planktothrix pseudagardhii]
MNIDTEILQMVGIMPESLKQELLHYANYLMENYSQKTPSEQPPVKKRRSGILQGTFVLPLSDDFDEPLEDFKEYME

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A7Z9BN42

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A7Z9BU65

References