Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-UPF0150
Location 2162328..2162734 Replicon chromosome
Accession NZ_LR882967
Organism Planktothrix pseudagardhii strain No.713

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag NMK36_RS09135 Protein ID WP_254173582.1
Coordinates 2162328..2162522 (+) Length 65 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag NMK36_RS09140 Protein ID WP_254173583.1
Coordinates 2162519..2162734 (+) Length 72 a.a.

Genomic Context

NMK36_RS09115NMK36_RS09120NMK36_RS09125NMK36_RS09130NMK36_RS09135NMK36_RS09140NMK36_RS09145NMK36_RS09150NMK36_RS09155NMK36_RS09160NMK36_RS09165
Location: 2158072..2158752 (681 bp)
Type: Others
Protein ID: WP_254173580.1
Location: 2160276..2160848 (573 bp)
Type: Others
Protein ID: Protein_1804
Location: 2160993..2161805 (813 bp)
Type: Others
Protein ID: Protein_1805
Location: 2162108..2162305 (198 bp)
Type: Others
Protein ID: WP_254173581.1
Location: 2162328..2162522 (195 bp)
Type: Toxin
Protein ID: WP_254173582.1
Location: 2162519..2162734 (216 bp)
Type: Antitoxin
Protein ID: WP_254173583.1
Location: 2162783..2163139 (357 bp)
Type: Others
Protein ID: WP_254173584.1
Location: 2163136..2164194 (1059 bp)
Type: Others
Protein ID: WP_254173585.1
Location: 2164216..2164362 (147 bp)
Type: Others
Protein ID: WP_254173586.1
Location: 2164593..2164901 (309 bp)
Type: Others
Protein ID: WP_197047482.1
Location: 2165051..2166280 (1230 bp)
Type: Others
Protein ID: WP_072721121.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NMK36_RS09115 (NO713_01821)2158072..2158752+681WP_254173580.1hypothetical protein-
NMK36_RS091202160276..2160848+573Protein_1804tetratricopeptide repeat protein-
NMK36_RS091252160993..2161805+813Protein_1805formylglycine-generating enzyme family protein-
NMK36_RS09130 (NO713_01823)2162108..2162305+198WP_254173581.1hypothetical protein-
NMK36_RS09135 (NO713_01824)2162328..2162522+195WP_254173582.1type II toxin-antitoxin system HicA family toxinToxin
NMK36_RS09140 (NO713_01825)2162519..2162734+216WP_254173583.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
NMK36_RS09145 (NO713_01826)2162783..2163139+357WP_254173584.1diversity-generating retroelement protein Avd-
NMK36_RS09150 (NO713_01827)2163136..2164194+1059WP_254173585.1RNA-directed DNA polymerase-
NMK36_RS091552164216..2164362+147WP_254173586.1SUMF1/EgtB/PvdO family nonheme iron enzyme-
NMK36_RS09160 (NO713_01828)2164593..2164901-309WP_197047482.130S ribosomal protein S10-
NMK36_RS09165 (NO713_01829)2165051..2166280-1230WP_072721121.1elongation factor Tu-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(4-60)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(7-62)


Sequences

Toxin        


Download         Length: 65 a.a.        Molecular weight: 7321.45 Da        Isoelectric Point: 9.8657

>T289990 WP_254173582.1 NZ_LR882967:2162328-2162522 [Planktothrix pseudagardhii]
MKVREVLKRLEADGWYEARMRGSHRVLKHPEKSGIVVVLGNFSDEVAIGTLKSIWKQAQLEDQS

Download         Length: 195 bp

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 7737.73 Da        Isoelectric Point: 4.0105

>AT289990 WP_254173583.1 NZ_LR882967:2162519-2162734 [Planktothrix pseudagardhii]
MKEYVAIFEWAGSNYSAYVPDLPGCISTGKTLEETANNIKEAIELYIDTLREDGQAIPEPSLTVKTISVAA

Download         Length: 216 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References