Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 2767526..2768003 Replicon chromosome
Accession NZ_LR882963
Organism Planktothrix agardhii strain No.66

Toxin (Protein)


Gene name - Uniprot ID A0A1J1JEC9
Locus tag NMG84_RS12460 Protein ID WP_042155864.1
Coordinates 2767731..2768003 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag NMG84_RS12455 Protein ID WP_254032383.1
Coordinates 2767526..2767750 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMG84_RS12420 (PANO66_02478) 2762879..2763355 - 477 WP_042155870.1 R3H domain-containing nucleic acid-binding protein -
NMG84_RS12425 (PANO66_02479) 2763358..2764515 - 1158 WP_042155869.1 membrane protein insertase YidC -
NMG84_RS12430 (PANO66_02480) 2764661..2765053 - 393 WP_227364941.1 PH domain-containing protein -
NMG84_RS12435 (PANO66_02481) 2765025..2765429 - 405 WP_042155868.1 ribonuclease P protein component -
NMG84_RS12440 (PANO66_02482) 2765539..2765676 - 138 WP_071783091.1 50S ribosomal protein L34 -
NMG84_RS12445 (PANO66_02483) 2765793..2766302 - 510 WP_026797999.1 DUF2808 domain-containing protein -
NMG84_RS12450 (PANO66_02484) 2766450..2767094 - 645 WP_227381268.1 Uma2 family endonuclease -
NMG84_RS12455 (PANO66_02485) 2767526..2767750 - 225 WP_254032383.1 CopG family antitoxin Antitoxin
NMG84_RS12460 (PANO66_02486) 2767731..2768003 - 273 WP_042155864.1 BrnT family toxin Toxin
NMG84_RS12465 (PANO66_02488) 2768783..2770873 + 2091 WP_227381269.1 DUF4352 domain-containing protein -
NMG84_RS12470 2770986..2771129 - 144 WP_227364946.1 hypothetical protein -
NMG84_RS12475 2771264..2771482 - 219 Protein_2454 IS701 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin

CopG antitoxin

(2-68)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10918.26 Da        Isoelectric Point: 7.2018

>T289985 WP_042155864.1 NZ_LR882963:c2768003-2767731 [Planktothrix agardhii]
MYSFEYDDNKSRTNQQKHGIDFIEAQQLWQDDDLLEIQATSETESRFLAIGKLKQKHWTAVITYRLENIRIISVRRSRPN
EVIWYESRRI

Download         Length: 273 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8703.86 Da        Isoelectric Point: 4.4764

>AT289985 WP_254032383.1 NZ_LR882963:c2767750-2767526 [Planktothrix agardhii]
MKAEEFDAKFETGEDLTEFMDFSTARRPNREKQKIELNLPLWMIRQLEAEAQKQGISPQTFLENYLAENLAPVR

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J1JEC9

Antitoxin

Source ID Structure

References