Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 2013924..2014486 Replicon chromosome
Accession NZ_LR882963
Organism Planktothrix agardhii strain No.66

Toxin (Protein)


Gene name vapC Uniprot ID A0A1J1JI02
Locus tag NMG84_RS08980 Protein ID WP_026786450.1
Coordinates 2014151..2014486 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1J1JJG5
Locus tag NMG84_RS08975 Protein ID WP_026786451.1
Coordinates 2013924..2014154 (+) Length 77 a.a.

Genomic Context

NMG84_RS08945NMG84_RS08960NMG84_RS08965NMG84_RS08970NMG84_RS08975NMG84_RS08980NMG84_RS08985NMG84_RS08995NMG84_RS09005NMG84_RS09010NMG84_RS09015NMG84_RS09020NMG84_RS08950NMG84_RS08955NMG84_RS08990NMG84_RS09000
Location: 2009130..2009711 (582 bp)
Type: Others
Protein ID: WP_254032275.1
Location: 2012528..2012827 (300 bp)
Type: Others
Protein ID: WP_026797899.1
Location: 2012981..2013382 (402 bp)
Type: Others
Protein ID: WP_227366197.1
Location: 2013665..2013922 (258 bp)
Type: Others
Protein ID: WP_254032277.1
Location: 2013924..2014154 (231 bp)
Type: Antitoxin
Protein ID: WP_026786451.1
Location: 2014151..2014486 (336 bp)
Type: Toxin
Protein ID: WP_026786450.1
Location: 2014701..2014997 (297 bp)
Type: Others
Protein ID: WP_254032278.1
Location: 2015689..2016060 (372 bp)
Type: Others
Protein ID: WP_254032704.1
Location: 2017375..2017557 (183 bp)
Type: Others
Protein ID: WP_254032279.1
Location: 2017903..2018352 (450 bp)
Type: Others
Protein ID: WP_042152432.1
Location: 2018349..2018720 (372 bp)
Type: Others
Protein ID: WP_026794176.1
Location: 2018741..2019169 (429 bp)
Type: Others
Protein ID: WP_227366191.1
Location: 2009786..2011888 (2103 bp)
Type: Others
Protein ID: WP_254032276.1
Location: 2011866..2012069 (204 bp)
Type: Others
Protein ID: WP_026797898.1
Location: 2014954..2015473 (520 bp)
Type: Others
Protein ID: Protein_1770
Location: 2016142..2017155 (1014 bp)
Type: Others
Protein ID: WP_042158409.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NMG84_RS08945 (PANO66_01785)2009130..2009711+582WP_254032275.1class I SAM-dependent methyltransferase-
NMG84_RS08950 (PANO66_01786)2009786..2011888-2103WP_254032276.1tetratricopeptide repeat protein-
NMG84_RS08955 (PANO66_01787)2011866..2012069-204WP_026797898.1hypothetical protein-
NMG84_RS08960 (PANO66_01788)2012528..2012827+300WP_026797899.1hypothetical protein-
NMG84_RS08965 (PANO66_01789)2012981..2013382+402WP_227366197.1type II toxin-antitoxin system VapC family toxin-
NMG84_RS08970 (PANO66_01790)2013665..2013922+258WP_254032277.1type II toxin-antitoxin system HicB family antitoxin-
NMG84_RS08975 (PANO66_01791)2013924..2014154+231WP_026786451.1DUF433 domain-containing proteinAntitoxin
NMG84_RS08980 (PANO66_01792)2014151..2014486+336WP_026786450.1DUF5615 family PIN-like proteinToxin
NMG84_RS08985 (PANO66_01793)2014701..2014997+297WP_254032278.1hypothetical protein-
NMG84_RS08990 (PANO66_01794)2014954..2015473-520Protein_1770hypothetical protein-
NMG84_RS08995 (PANO66_01795)2015689..2016060+372WP_254032704.1Uma2 family endonuclease-
NMG84_RS09000 (PANO66_01796)2016142..2017155-1014WP_042158409.1IS701-like element ISPlag1 family transposase-
NMG84_RS09005 (PANO66_01797)2017375..2017557+183WP_254032279.1hypothetical protein-
NMG84_RS09010 (PANO66_01798)2017903..2018352+450WP_042152432.1DUF29 domain-containing protein-
NMG84_RS09015 (PANO66_01799)2018349..2018720+372WP_026794176.1nucleotidyltransferase domain-containing protein-
NMG84_RS09020 (PANO66_01800)2018741..2019169+429WP_227366191.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(10-65)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12268.99 Da        Isoelectric Point: 3.9823

>T289984 WP_026786450.1 NZ_LR882963:2014151-2014486 [Planktothrix agardhii]
MNFWIDAQLPPSLANWLVETFNVNATAIRDLGLRDAEDIEIFNAARNPGTVIVSKDSDFVELVTRLGTPPQILWLTCGNV
TNRNLRLILSNTFAEALPMLEAGEAIVEISD

Download         Length: 336 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8535.94 Da        Isoelectric Point: 6.2230

>AT289984 WP_026786451.1 NZ_LR882963:2013924-2014154 [Planktothrix agardhii]
MTAKSLLNRITYNPRQCGGRPCIRGMRIRVSDILEMLAENVSSGEILEDFPDLEAEDIQACLLFAARRTNIPKLTV

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1J1JI02

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1J1JJG5

References