Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-PHD
Location 3638806..3639462 Replicon chromosome
Accession NZ_LR882952
Organism Planktothrix agardhii strain No.976

Toxin (Protein)


Gene name vapC Uniprot ID A0A4P5ZG20
Locus tag NMG88_RS16905 Protein ID WP_026798539.1
Coordinates 3639064..3639462 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1J1J9N3
Locus tag NMG88_RS16900 Protein ID WP_026795934.1
Coordinates 3638806..3639051 (+) Length 82 a.a.

Genomic Context

NMG88_RS16855NMG88_RS16860NMG88_RS16865NMG88_RS16875NMG88_RS16880NMG88_RS16900NMG88_RS16905NMG88_RS16925NMG88_RS16870NMG88_RS16885NMG88_RS16890NMG88_RS16895NMG88_RS16910NMG88_RS16915NMG88_RS16920NMG88_RS16930NMG88_RS16935NMG88_RS16940
Location: 3634479..3635174 (696 bp)
Type: Others
Protein ID: WP_026785406.1
Location: 3635347..3635910 (564 bp)
Type: Others
Protein ID: WP_227350526.1
Location: 3636567..3636782 (216 bp)
Type: Others
Protein ID: WP_036831945.1
Location: 3637079..3637354 (276 bp)
Type: Others
Protein ID: WP_235751408.1
Location: 3637351..3637671 (321 bp)
Type: Others
Protein ID: WP_235751407.1
Location: 3638806..3639051 (246 bp)
Type: Antitoxin
Protein ID: WP_026795934.1
Location: 3639064..3639462 (399 bp)
Type: Toxin
Protein ID: WP_026798539.1
Location: 3641284..3642657 (1374 bp)
Type: Others
Protein ID: WP_254035641.1
Location: 3636925..3637080 (156 bp)
Type: Others
Protein ID: WP_167541238.1
Location: 3637678..3637902 (225 bp)
Type: Others
Protein ID: WP_237747547.1
Location: 3637969..3638373 (405 bp)
Type: Others
Protein ID: WP_026785412.1
Location: 3638376..3638624 (249 bp)
Type: Others
Protein ID: WP_036831938.1
Location: 3639619..3640002 (384 bp)
Type: Others
Protein ID: WP_026785416.1
Location: 3639995..3640237 (243 bp)
Type: Others
Protein ID: WP_235751405.1
Location: 3640477..3641070 (594 bp)
Type: Others
Protein ID: WP_027255350.1
Location: 3642688..3643074 (387 bp)
Type: Others
Protein ID: WP_227365720.1
Location: 3643076..3643318 (243 bp)
Type: Others
Protein ID: WP_227365722.1
Location: 3643549..3644442 (894 bp)
Type: Others
Protein ID: WP_042153928.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NMG88_RS16855 (NO976_03374)3634479..3635174+696WP_026785406.1response regulator transcription factor-
NMG88_RS16860 (NO976_03375)3635347..3635910+564WP_227350526.1DUF192 domain-containing protein-
NMG88_RS16865 (NO976_03376)3636567..3636782+216WP_036831945.1DUF2949 domain-containing protein-
NMG88_RS168703636925..3637080-156WP_167541238.1hypothetical protein-
NMG88_RS16875 (NO976_03378)3637079..3637354+276WP_235751408.1hypothetical protein-
NMG88_RS16880 (NO976_03379)3637351..3637671+321WP_235751407.1type II toxin-antitoxin system VapC family toxin-
NMG88_RS168853637678..3637902-225WP_237747547.1hypothetical protein-
NMG88_RS16890 (NO976_03381)3637969..3638373-405WP_026785412.1PIN domain-containing protein-
NMG88_RS16895 (NO976_03382)3638376..3638624-249WP_036831938.1AbrB/MazE/SpoVT family DNA-binding domain-containing protein-
NMG88_RS16900 (NO976_03383)3638806..3639051+246WP_026795934.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
NMG88_RS16905 (NO976_03384)3639064..3639462+399WP_026798539.1type II toxin-antitoxin system VapC family toxinToxin
NMG88_RS16910 (NO976_03385)3639619..3640002-384WP_026785416.1type II toxin-antitoxin system VapC family toxin-
NMG88_RS16915 (NO976_03386)3639995..3640237-243WP_235751405.1hypothetical protein-
NMG88_RS16920 (NO976_03387)3640477..3641070-594WP_027255350.1hypothetical protein-
NMG88_RS16925 (NO976_03388)3641284..3642657+1374WP_254035641.1NB-ARC domain-containing protein-
NMG88_RS16930 (NO976_03389)3642688..3643074-387WP_227365720.1type II toxin-antitoxin system VapC family toxin-
NMG88_RS16935 (NO976_03390)3643076..3643318-243WP_227365722.1hypothetical protein-
NMG88_RS16940 (NO976_03391)3643549..3644442-894WP_042153928.1acetylglutamate kinase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

VapC-like Sll0205 protein, PIN domain

(4-129)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-45)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15305.73 Da        Isoelectric Point: 5.1406

>T289983 WP_026798539.1 NZ_LR882952:3639064-3639462 [Planktothrix agardhii]
VKLLLDTQCWLWWFAQPERLNQEVIAQIADESNELWFSVASVWEIGIKVAIRKLPLPEPIDTYISSRMVQLDMRYLEIKA
PHALRSSALPLHHRDPFDRMLIAQAQIENMTLVSADSIFKQYSDISVLWAAN

Download         Length: 399 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9077.41 Da        Isoelectric Point: 4.5358

>AT289983 WP_026795934.1 NZ_LR882952:3638806-3639051 [Planktothrix agardhii]
MAKLQIENLPNDFKKNLSELLSRVELGEEIIISNQGVAIAKLIPFRPSSNRRASLGQDQGKFIIPDDFNEPLPQEILAAF
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A4P5ZG20

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1J1J9N3

References