289980

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 1504374..1505428 Replicon chromosome
Accession NZ_LR882952
Organism Planktothrix agardhii strain No.976

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag NMG88_RS07070 Protein ID WP_278047053.1
Coordinates 1504859..1505428 (+) Length 190 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag NMG88_RS07065 Protein ID WP_254035251.1
Coordinates 1504374..1504859 (+) Length 162 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMG88_RS07025 (NO976_01412) 1499663..1499875 - 213 WP_042153010.1 hypothetical protein -
NMG88_RS07030 (NO976_01413) 1500024..1500353 + 330 WP_227350328.1 type II toxin-antitoxin system RelE/ParE family toxin -
NMG88_RS07035 (NO976_01414) 1500340..1500699 + 360 WP_042153014.1 hypothetical protein -
NMG88_RS07040 (NO976_01415) 1500812..1501027 + 216 WP_042153017.1 hypothetical protein -
NMG88_RS07050 (NO976_01417) 1501522..1502442 + 921 WP_042153018.1 glutaminase A -
NMG88_RS07055 (NO976_01418) 1502618..1503526 + 909 WP_227366019.1 pentapeptide repeat-containing protein -
NMG88_RS07060 (NO976_01419) 1503554..1503877 + 324 WP_042153022.1 divalent-cation tolerance protein CutA -
NMG88_RS07065 (NO976_01420) 1504374..1504859 + 486 WP_254035251.1 helix-turn-helix domain-containing protein Antitoxin
NMG88_RS07070 (NO976_01421) 1504859..1505428 + 570 WP_278047053.1 PIN domain-containing protein Toxin
NMG88_RS07075 (NO976_01422) 1505586..1507298 + 1713 WP_254035253.1 DUF262 domain-containing protein -
NMG88_RS07080 (NO976_01423) 1507507..1507755 + 249 WP_254035254.1 DUF2281 domain-containing protein -
NMG88_RS07085 (NO976_01424) 1507752..1508168 + 417 WP_254035255.1 PIN domain-containing protein -
NMG88_RS07090 (NO976_01425) 1508155..1508394 - 240 WP_254035256.1 hypothetical protein -
NMG88_RS07095 (NO976_01426) 1508387..1508686 - 300 WP_254035257.1 hypothetical protein -
NMG88_RS07100 1508685..1508828 + 144 WP_254035258.1 hypothetical protein -
NMG88_RS07105 (NO976_01427) 1508873..1509232 + 360 WP_227350331.1 hypothetical protein -
NMG88_RS07110 (NO976_01428) 1509229..1509648 + 420 WP_254033364.1 HNH endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-112)

Antitoxin

Helix-turn-helix domain, group 17

(87-134)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21513.77 Da        Isoelectric Point: 4.6188

>T289980 WP_278047053.1 NZ_LR882952:1504859-1505428 [Planktothrix agardhii]
VANFSVVYDACVLYPAPLRDFLMELAITDLFKALWTDAIHDEWIRNVLKNRPDLTLEQLTRTKTLMNSHVRDCLVTGYED
LILGLQLPDPDDRHVLAAAIRCNADVIVTFNLDDFPSQALQQYGVEAQHPDEFILHLLDLNPAMVCRAAEIQRIRLKNPP
KTPDEYLDTLLKQGLPQSVSTLRELCYGI

Download         Length: 570 bp

>T289980 NZ_LR882952:1504859-1505428 [Planktothrix agardhii]
GTGGCTAATTTTTCCGTTGTCTACGATGCTTGTGTTTTATATCCAGCACCGCTTCGTGATTTTTTAATGGAACTTGCCAT
CACTGACTTATTTAAGGCACTTTGGACAGATGCTATTCACGATGAATGGATCAGAAATGTTCTCAAAAATCGTCCTGATC
TTACACTTGAACAGCTTACCAGGACTAAAACTCTGATGAATTCTCATGTTAGAGATTGCCTGGTTACAGGATACGAAGAC
CTAATATTAGGATTACAACTTCCTGATCCAGATGATCGTCATGTTCTTGCTGCTGCCATTCGCTGTAATGCTGATGTAAT
TGTCACTTTTAATCTTGATGATTTTCCCAGTCAAGCACTTCAACAATATGGTGTTGAAGCGCAGCACCCGGATGAGTTTA
TTCTACACTTACTCGACTTGAACCCAGCAATGGTCTGTAGAGCAGCCGAAATACAACGAATCAGACTTAAAAATCCACCT
AAAACACCTGATGAATATCTGGACACGCTTCTAAAACAAGGACTTCCGCAGTCCGTGAGTACGTTAAGGGAGTTGTGTTA
TGGAATTTAG

Antitoxin


Download         Length: 162 a.a.        Molecular weight: 18082.67 Da        Isoelectric Point: 4.8582

>AT289980 WP_254035251.1 NZ_LR882952:1504374-1504859 [Planktothrix agardhii]
MTLTEAPNLRSVLPTEEEATIAQASSSSLARYIKNQDGCTRTIKLVQDDSQDEVVVIPAEAFRLLLEMLAQMAKGNAVTL
IPIHAELTTQEAADILNVSRPYLVQLLESGEIPFRKVGTRRRVRYQDLMDYKNRVDAARRKTLDELTTQAQELNMGYEGV
M

Download         Length: 486 bp

>AT289980 NZ_LR882952:1504374-1504859 [Planktothrix agardhii]
ATGACACTTACAGAGGCTCCAAACTTGCGGTCTGTTCTACCTACGGAAGAAGAAGCTACGATTGCACAAGCCAGTAGCTC
GTCTTTGGCACGGTACATCAAGAACCAAGACGGATGCACCCGTACCATCAAGCTTGTGCAAGATGACAGCCAAGATGAAG
TTGTTGTCATACCTGCTGAAGCTTTTCGTCTACTGCTTGAGATGTTGGCACAGATGGCGAAGGGAAATGCTGTAACGCTG
ATTCCAATTCACGCAGAACTTACCACCCAAGAAGCTGCTGACATTTTGAATGTTTCCCGTCCCTATTTGGTGCAACTGCT
GGAGTCTGGAGAAATCCCTTTTCGTAAAGTGGGTACGCGCCGAAGGGTGCGTTACCAAGATTTAATGGACTACAAAAATC
GAGTTGATGCAGCACGACGGAAAACTCTTGATGAGCTTACTACTCAAGCTCAAGAACTGAATATGGGATACGAAGGAGTC
ATGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References