Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 1124030..1124592 Replicon chromosome
Accession NZ_LR882952
Organism Planktothrix agardhii strain No.976

Toxin (Protein)


Gene name vapC Uniprot ID A0A1J1JI02
Locus tag NMG88_RS05235 Protein ID WP_026786450.1
Coordinates 1124257..1124592 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1J1JJG5
Locus tag NMG88_RS05230 Protein ID WP_026786451.1
Coordinates 1124030..1124260 (+) Length 77 a.a.

Genomic Context

NMG88_RS05200NMG88_RS05205NMG88_RS05210NMG88_RS05215NMG88_RS05225NMG88_RS05230NMG88_RS05235NMG88_RS05240NMG88_RS05245NMG88_RS05250NMG88_RS05255NMG88_RS05265NMG88_RS05220NMG88_RS05260
Location: 1120206..1120775 (570 bp)
Type: Others
Protein ID: WP_202807045.1
Location: 1120765..1121688 (924 bp)
Type: Others
Protein ID: WP_254035182.1
Location: 1121862..1122119 (258 bp)
Type: Others
Protein ID: WP_254035183.1
Location: 1122172..1122498 (327 bp)
Type: Others
Protein ID: WP_254035184.1
Location: 1123888..1124028 (141 bp)
Type: Others
Protein ID: WP_227357797.1
Location: 1124030..1124260 (231 bp)
Type: Antitoxin
Protein ID: WP_026786451.1
Location: 1124257..1124592 (336 bp)
Type: Toxin
Protein ID: WP_026786450.1
Location: 1124807..1125535 (729 bp)
Type: Others
Protein ID: WP_235751126.1
Location: 1125881..1126330 (450 bp)
Type: Others
Protein ID: WP_042152432.1
Location: 1126327..1126698 (372 bp)
Type: Others
Protein ID: WP_026794176.1
Location: 1126719..1127147 (429 bp)
Type: Others
Protein ID: WP_227366191.1
Location: 1127922..1129199 (1278 bp)
Type: Others
Protein ID: WP_254035185.1
Location: 1122463..1123385 (923 bp)
Type: Others
Protein ID: Protein_1031
Location: 1127190..1127834 (645 bp)
Type: Others
Protein ID: WP_026786446.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NMG88_RS05200 (NO976_01041)1120206..1120775+570WP_202807045.1GNAT family protein-
NMG88_RS05205 (NO976_01042)1120765..1121688+924WP_254035182.1hypothetical protein-
NMG88_RS05210 (NO976_01043)1121862..1122119+258WP_254035183.1N-acetylneuraminate synthase family protein-
NMG88_RS05215 (NO976_01044)1122172..1122498+327WP_254035184.1hypothetical protein-
NMG88_RS05220 (NO976_01045)1122463..1123385-923Protein_1031IS4 family transposase-
NMG88_RS05225 (NO976_01047)1123888..1124028+141WP_227357797.1hypothetical protein-
NMG88_RS05230 (NO976_01048)1124030..1124260+231WP_026786451.1DUF433 domain-containing proteinAntitoxin
NMG88_RS05235 (NO976_01049)1124257..1124592+336WP_026786450.1DUF5615 family PIN-like proteinToxin
NMG88_RS05240 (NO976_01050)1124807..1125535+729WP_235751126.1Uma2 family endonuclease-
NMG88_RS05245 (NO976_01051)1125881..1126330+450WP_042152432.1DUF29 domain-containing protein-
NMG88_RS05250 (NO976_01052)1126327..1126698+372WP_026794176.1nucleotidyltransferase domain-containing protein-
NMG88_RS05255 (NO976_01053)1126719..1127147+429WP_227366191.1hypothetical protein-
NMG88_RS05260 (NO976_01054)1127190..1127834-645WP_026786446.1Uma2 family endonuclease-
NMG88_RS05265 (NO976_01055)1127922..1129199+1278WP_254035185.1FkbM family methyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--1122463..1123080617


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(10-65)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12268.99 Da        Isoelectric Point: 3.9823

>T289979 WP_026786450.1 NZ_LR882952:1124257-1124592 [Planktothrix agardhii]
MNFWIDAQLPPSLANWLVETFNVNATAIRDLGLRDAEDIEIFNAARNPGTVIVSKDSDFVELVTRLGTPPQILWLTCGNV
TNRNLRLILSNTFAEALPMLEAGEAIVEISD

Download         Length: 336 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8535.94 Da        Isoelectric Point: 6.2230

>AT289979 WP_026786451.1 NZ_LR882952:1124030-1124260 [Planktothrix agardhii]
MTAKSLLNRITYNPRQCGGRPCIRGMRIRVSDILEMLAENVSSGEILEDFPDLEAEDIQACLLFAARRTNIPKLTV

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1J1JI02

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1J1JJG5

References