Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 4508716..4509226 Replicon chromosome
Accession NZ_LR882950
Organism Planktothrix agardhii strain PCC7805

Toxin (Protein)


Gene name relB Uniprot ID A0A1J1J9S6
Locus tag NMG85_RS20525 Protein ID WP_027255358.1
Coordinates 4508716..4508979 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A1J1JAK8
Locus tag NMG85_RS20530 Protein ID WP_026785375.1
Coordinates 4508972..4509226 (-) Length 85 a.a.

Genomic Context

NMG85_RS20500NMG85_RS20505NMG85_RS20515NMG85_RS20510NMG85_RS20520NMG85_RS20525NMG85_RS20530NMG85_RS20535NMG85_RS20540NMG85_RS20545NMG85_RS20550NMG85_RS20555
Location: 4504157..4504732 (576 bp)
Type: Others
Protein ID: WP_227397778.1
Location: 4504736..4506445 (1710 bp)
Type: Others
Protein ID: WP_227397777.1
Location: 4508085..4508216 (132 bp)
Type: Others
Protein ID: WP_026796378.1
Location: 4506591..4507808 (1218 bp)
Type: Others
Protein ID: WP_227350540.1
Location: 4508259..4508660 (402 bp)
Type: Others
Protein ID: WP_254034872.1
Location: 4508716..4508979 (264 bp)
Type: Toxin
Protein ID: WP_027255358.1
Location: 4508972..4509226 (255 bp)
Type: Antitoxin
Protein ID: WP_026785375.1
Location: 4509402..4509875 (474 bp)
Type: Others
Protein ID: WP_227357893.1
Location: 4509963..4511684 (1722 bp)
Type: Others
Protein ID: WP_254034873.1
Location: 4511695..4512234 (540 bp)
Type: Others
Protein ID: WP_042153957.1
Location: 4512338..4513027 (690 bp)
Type: Others
Protein ID: WP_227350534.1
Location: 4513291..4513866 (576 bp)
Type: Others
Protein ID: WP_254034874.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NMG85_RS20500 (PCC7805_04113)4504157..4504732+576WP_227397778.1hypothetical protein-
NMG85_RS20505 (PCC7805_04114)4504736..4506445+1710WP_227397777.1hypothetical protein-
NMG85_RS20510 (PCC7805_04115)4506591..4507808-1218WP_227350540.1glycosyltransferase family 4 protein-
NMG85_RS20515 (PCC7805_04116)4508085..4508216+132WP_026796378.1photosystem II reaction center protein Ycf12-
NMG85_RS20520 (PCC7805_04117)4508259..4508660-402WP_254034872.1DUF4346 domain-containing protein-
NMG85_RS20525 (PCC7805_04118)4508716..4508979-264WP_027255358.1Txe/YoeB family addiction module toxinToxin
NMG85_RS20530 (PCC7805_04119)4508972..4509226-255WP_026785375.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
NMG85_RS20535 (PCC7805_04120)4509402..4509875-474WP_227357893.1hypothetical protein-
NMG85_RS20540 (PCC7805_04121)4509963..4511684-1722WP_254034873.1solute carrier family 26 protein-
NMG85_RS20545 (PCC7805_04122)4511695..4512234-540WP_042153957.1rhodanese-like domain-containing protein-
NMG85_RS20550 (PCC7805_04123)4512338..4513027-690WP_227350534.1MBL fold metallo-hydrolase-
NMG85_RS20555 (PCC7805_04124)4513291..4513866-576WP_254034874.1Uma2 family endonuclease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10554.09 Da        Isoelectric Point: 9.3327

>T289977 WP_027255358.1 NZ_LR882950:c4508979-4508716 [Planktothrix agardhii]
MSNRILAWTDEAWDNYIYWQNQDRKTLKKINKLLDAIKKRPFEGIGKPEPLKENLSGFWSRRIDDTNRLVYVVDDLYITI
ISCRYHY

Download         Length: 264 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9524.84 Da        Isoelectric Point: 6.0673

>AT289977 WP_026785375.1 NZ_LR882950:c4509226-4508972 [Planktothrix agardhii]
MKVVTFSEAKSQLKTVLDRVVEDADYTIITRRDADHAVVMSLDYFNGLLETVHLLKSPANAAHLERSIAQYRQGKALEHQ
LIDE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1J1J9S6

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1J1JAK8

References