Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 4508716..4509226 Replicon chromosome
Accession NZ_LR882950
Organism Planktothrix agardhii strain PCC7805

Toxin (Protein)


Gene name relB Uniprot ID A0A1J1J9S6
Locus tag NMG85_RS20525 Protein ID WP_027255358.1
Coordinates 4508716..4508979 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A1J1JAK8
Locus tag NMG85_RS20530 Protein ID WP_026785375.1
Coordinates 4508972..4509226 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMG85_RS20500 (PCC7805_04113) 4504157..4504732 + 576 WP_227397778.1 hypothetical protein -
NMG85_RS20505 (PCC7805_04114) 4504736..4506445 + 1710 WP_227397777.1 hypothetical protein -
NMG85_RS20510 (PCC7805_04115) 4506591..4507808 - 1218 WP_227350540.1 glycosyltransferase family 4 protein -
NMG85_RS20515 (PCC7805_04116) 4508085..4508216 + 132 WP_026796378.1 photosystem II reaction center protein Ycf12 -
NMG85_RS20520 (PCC7805_04117) 4508259..4508660 - 402 WP_254034872.1 DUF4346 domain-containing protein -
NMG85_RS20525 (PCC7805_04118) 4508716..4508979 - 264 WP_027255358.1 Txe/YoeB family addiction module toxin Toxin
NMG85_RS20530 (PCC7805_04119) 4508972..4509226 - 255 WP_026785375.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NMG85_RS20535 (PCC7805_04120) 4509402..4509875 - 474 WP_227357893.1 hypothetical protein -
NMG85_RS20540 (PCC7805_04121) 4509963..4511684 - 1722 WP_254034873.1 solute carrier family 26 protein -
NMG85_RS20545 (PCC7805_04122) 4511695..4512234 - 540 WP_042153957.1 rhodanese-like domain-containing protein -
NMG85_RS20550 (PCC7805_04123) 4512338..4513027 - 690 WP_227350534.1 MBL fold metallo-hydrolase -
NMG85_RS20555 (PCC7805_04124) 4513291..4513866 - 576 WP_254034874.1 Uma2 family endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10554.09 Da        Isoelectric Point: 9.3327

>T289977 WP_027255358.1 NZ_LR882950:c4508979-4508716 [Planktothrix agardhii]
MSNRILAWTDEAWDNYIYWQNQDRKTLKKINKLLDAIKKRPFEGIGKPEPLKENLSGFWSRRIDDTNRLVYVVDDLYITI
ISCRYHY

Download         Length: 264 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9524.84 Da        Isoelectric Point: 6.0673

>AT289977 WP_026785375.1 NZ_LR882950:c4509226-4508972 [Planktothrix agardhii]
MKVVTFSEAKSQLKTVLDRVVEDADYTIITRRDADHAVVMSLDYFNGLLETVHLLKSPANAAHLERSIAQYRQGKALEHQ
LIDE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J1J9S6

Antitoxin

Source ID Structure
AlphaFold DB A0A1J1JAK8

References