Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 1355590..1356152 Replicon chromosome
Accession NZ_LR882950
Organism Planktothrix agardhii strain PCC7805

Toxin (Protein)


Gene name vapC Uniprot ID A0A1J1JI02
Locus tag NMG85_RS05895 Protein ID WP_026786450.1
Coordinates 1355590..1355925 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1J1JJG5
Locus tag NMG85_RS05900 Protein ID WP_026786451.1
Coordinates 1355922..1356152 (-) Length 77 a.a.

Genomic Context

NMG85_RS05865NMG85_RS05920NMG85_RS05925NMG85_RS05930NMG85_RS05870NMG85_RS05875NMG85_RS05880NMG85_RS05885NMG85_RS05890NMG85_RS05895NMG85_RS05900NMG85_RS05905NMG85_RS05910NMG85_RS05915
Location: 1351041..1351685 (645 bp)
Type: Others
Protein ID: WP_227350210.1
Location: 1358011..1358217 (207 bp)
Type: Others
Protein ID: WP_141295995.1
Location: 1358261..1358482 (222 bp)
Type: Others
Protein ID: WP_026786454.1
Location: 1358536..1360152 (1617 bp)
Type: Others
Protein ID: WP_254034383.1
Location: 1351728..1352018 (291 bp)
Type: Others
Protein ID: WP_052338730.1
Location: 1352098..1353270 (1173 bp)
Type: Others
Protein ID: WP_254034382.1
Location: 1353484..1353855 (372 bp)
Type: Others
Protein ID: WP_026794176.1
Location: 1353852..1354301 (450 bp)
Type: Others
Protein ID: WP_042152432.1
Location: 1354647..1355375 (729 bp)
Type: Others
Protein ID: WP_235751126.1
Location: 1355590..1355925 (336 bp)
Type: Toxin
Protein ID: WP_026786450.1
Location: 1355922..1356152 (231 bp)
Type: Antitoxin
Protein ID: WP_026786451.1
Location: 1356154..1356294 (141 bp)
Type: Others
Protein ID: WP_227366195.1
Location: 1356695..1357096 (402 bp)
Type: Others
Protein ID: WP_227366197.1
Location: 1357250..1357549 (300 bp)
Type: Others
Protein ID: WP_026797899.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NMG85_RS05865 (PCC7805_01180)1351041..1351685+645WP_227350210.1Uma2 family endonuclease-
NMG85_RS05870 (PCC7805_01181)1351728..1352018-291WP_052338730.1hypothetical protein-
NMG85_RS05875 (PCC7805_01182)1352098..1353270-1173WP_254034382.1transposase-
NMG85_RS05880 (PCC7805_01184)1353484..1353855-372WP_026794176.1nucleotidyltransferase domain-containing protein-
NMG85_RS05885 (PCC7805_01185)1353852..1354301-450WP_042152432.1DUF29 domain-containing protein-
NMG85_RS05890 (PCC7805_01186)1354647..1355375-729WP_235751126.1Uma2 family endonuclease-
NMG85_RS05895 (PCC7805_01187)1355590..1355925-336WP_026786450.1DUF5615 family PIN-like proteinToxin
NMG85_RS05900 (PCC7805_01188)1355922..1356152-231WP_026786451.1DUF433 domain-containing proteinAntitoxin
NMG85_RS05905 (PCC7805_01189)1356154..1356294-141WP_227366195.1hypothetical protein-
NMG85_RS05910 (PCC7805_01190)1356695..1357096-402WP_227366197.1type II toxin-antitoxin system VapC family toxin-
NMG85_RS05915 (PCC7805_01191)1357250..1357549-300WP_026797899.1hypothetical protein-
NMG85_RS05920 (PCC7805_01192)1358011..1358217+207WP_141295995.1hypothetical protein-
NMG85_RS05925 (PCC7805_01193)1358261..1358482+222WP_026786454.1type II toxin-antitoxin system HicB family antitoxin-
NMG85_RS05930 (PCC7805_01194)1358536..1360152+1617WP_254034383.1tetratricopeptide repeat protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--1352098..13532701172


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(10-65)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12268.99 Da        Isoelectric Point: 3.9823

>T289974 WP_026786450.1 NZ_LR882950:c1355925-1355590 [Planktothrix agardhii]
MNFWIDAQLPPSLANWLVETFNVNATAIRDLGLRDAEDIEIFNAARNPGTVIVSKDSDFVELVTRLGTPPQILWLTCGNV
TNRNLRLILSNTFAEALPMLEAGEAIVEISD

Download         Length: 336 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8535.94 Da        Isoelectric Point: 6.2230

>AT289974 WP_026786451.1 NZ_LR882950:c1356152-1355922 [Planktothrix agardhii]
MTAKSLLNRITYNPRQCGGRPCIRGMRIRVSDILEMLAENVSSGEILEDFPDLEAEDIQACLLFAARRTNIPKLTV

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A1J1JI02

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A1J1JJG5

References