Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 3245664..3246141 Replicon chromosome
Accession NZ_LR882944
Organism Planktothrix agardhii strain No.365

Toxin (Protein)


Gene name - Uniprot ID A0A1J1JEC9
Locus tag NMG87_RS14525 Protein ID WP_042155864.1
Coordinates 3245869..3246141 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1J1JHM1
Locus tag NMG87_RS14520 Protein ID WP_042155865.1
Coordinates 3245664..3245888 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMG87_RS14485 (NO365_02916) 3241920..3242312 - 393 WP_227364941.1 PH domain-containing protein -
NMG87_RS14490 (NO365_02917) 3242284..3242688 - 405 WP_042155868.1 ribonuclease P protein component -
NMG87_RS14495 (NO365_02918) 3242798..3242935 - 138 WP_071783091.1 50S ribosomal protein L34 -
NMG87_RS14500 (NO365_02919) 3243052..3243561 - 510 WP_026797999.1 DUF2808 domain-containing protein -
NMG87_RS14505 (NO365_02920) 3243897..3244139 + 243 WP_026786216.1 hypothetical protein -
NMG87_RS14510 (NO365_02922) 3244263..3244910 - 648 WP_254033714.1 Uma2 family endonuclease -
NMG87_RS14515 (NO365_02923) 3245101..3245442 - 342 WP_235766172.1 DUF433 domain-containing protein -
NMG87_RS14520 (NO365_02925) 3245664..3245888 - 225 WP_042155865.1 CopG family antitoxin Antitoxin
NMG87_RS14525 (NO365_02926) 3245869..3246141 - 273 WP_042155864.1 BrnT family toxin Toxin
NMG87_RS14530 (NO365_02928) 3247200..3249290 + 2091 WP_235751906.1 DUF4352 domain-containing protein -
NMG87_RS14535 3249357..3249494 + 138 WP_235751905.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin

CopG antitoxin

(3-68)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10918.26 Da        Isoelectric Point: 7.2018

>T289973 WP_042155864.1 NZ_LR882944:c3246141-3245869 [Planktothrix agardhii]
MYSFEYDDNKSRTNQQKHGIDFIEAQQLWQDDDLLEIQATSETESRFLAIGKLKQKHWTAVITYRLENIRIISVRRSRPN
EVIWYESRRI

Download         Length: 273 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8689.84 Da        Isoelectric Point: 4.4633

>AT289973 WP_042155865.1 NZ_LR882944:c3245888-3245664 [Planktothrix agardhii]
MKAEEFDAKFDTGEDLTEFMDFSTARRPNREKQKIELNLPLWMIRQLEAEAQKQGISPQTFLENYLAENLAPVR

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J1JEC9

Antitoxin

Source ID Structure
AlphaFold DB A0A1J1JHM1

References