Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 1809423..1809985 Replicon chromosome
Accession NZ_LR882944
Organism Planktothrix agardhii strain No.365

Toxin (Protein)


Gene name vapC Uniprot ID A0A1J1JI02
Locus tag NMG87_RS07750 Protein ID WP_026786450.1
Coordinates 1809423..1809758 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1J1JJG5
Locus tag NMG87_RS07755 Protein ID WP_026786451.1
Coordinates 1809755..1809985 (-) Length 77 a.a.

Genomic Context


NMG87_RS07725NMG87_RS07775NMG87_RS07790NMG87_RS07795NMG87_RS07720NMG87_RS07730NMG87_RS07735NMG87_RS07740NMG87_RS07745NMG87_RS07750NMG87_RS07755NMG87_RS07760NMG87_RS07765NMG87_RS07770NMG87_RS07780NMG87_RS07785
Location: 1806181..1806825 (645 bp)
Type: Others
Protein ID: WP_254033425.1
Location: 1811843..1812046 (204 bp)
Type: Others
Protein ID: WP_141296006.1
Location: 1813321..1813527 (207 bp)
Type: Others
Protein ID: WP_141295995.1
Location: 1813571..1813792 (222 bp)
Type: Others
Protein ID: WP_026786454.1
Location: 1804606..1806093 (1488 bp)
Type: Others
Protein ID: WP_254033424.1
Location: 1806868..1807296 (429 bp)
Type: Others
Protein ID: WP_227366191.1
Location: 1807317..1807688 (372 bp)
Type: Others
Protein ID: WP_026794176.1
Location: 1807685..1808134 (450 bp)
Type: Others
Protein ID: WP_036833930.1
Location: 1808480..1809208 (729 bp)
Type: Others
Protein ID: WP_254033426.1
Location: 1809423..1809758 (336 bp)
Type: Toxin
Protein ID: WP_026786450.1
Location: 1809755..1809985 (231 bp)
Type: Antitoxin
Protein ID: WP_026786451.1
Location: 1809987..1810127 (141 bp)
Type: Others
Protein ID: WP_227366195.1
Location: 1810528..1810929 (402 bp)
Type: Others
Protein ID: WP_026786452.1
Location: 1811082..1811381 (300 bp)
Type: Others
Protein ID: WP_026786453.1
Location: 1812087..1812314 (228 bp)
Type: Others
Protein ID: WP_141296003.1
Location: 1812318..1812792 (475 bp)
Type: Others
Protein ID: Protein_1531
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NMG87_RS07720 (NO365_01562)1804606..1806093-1488WP_254033424.1FkbM family methyltransferase-
NMG87_RS07725 (NO365_01563)1806181..1806825+645WP_254033425.1Uma2 family endonuclease-
NMG87_RS07730 (NO365_01564)1806868..1807296-429WP_227366191.1hypothetical protein-
NMG87_RS07735 (NO365_01565)1807317..1807688-372WP_026794176.1nucleotidyltransferase domain-containing protein-
NMG87_RS07740 (NO365_01566)1807685..1808134-450WP_036833930.1DUF29 domain-containing protein-
NMG87_RS07745 (NO365_01567)1808480..1809208-729WP_254033426.1Uma2 family endonuclease-
NMG87_RS07750 (NO365_01568)1809423..1809758-336WP_026786450.1DUF5615 family PIN-like proteinToxin
NMG87_RS07755 (NO365_01569)1809755..1809985-231WP_026786451.1DUF433 domain-containing proteinAntitoxin
NMG87_RS07760 (NO365_01570)1809987..1810127-141WP_227366195.1hypothetical protein-
NMG87_RS07765 (NO365_01571)1810528..1810929-402WP_026786452.1type II toxin-antitoxin system VapC family toxin-
NMG87_RS07770 (NO365_01573)1811082..1811381-300WP_026786453.1hypothetical protein-
NMG87_RS07775 (NO365_01574)1811843..1812046+204WP_141296006.1hypothetical protein-
NMG87_RS07780 (NO365_01575)1812087..1812314-228WP_141296003.1hypothetical protein-
NMG87_RS07785 (NO365_01576)1812318..1812792-475Protein_1531type II toxin-antitoxin system VapC family toxin-
NMG87_RS07790 (NO365_01577)1813321..1813527+207WP_141295995.1hypothetical protein-
NMG87_RS07795 (NO365_01578)1813571..1813792+222WP_026786454.1type II toxin-antitoxin system HicB family antitoxin-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-78)

Antitoxin

(10-65)


Sequences


Toxin        


Download         Length: 112 a.a.        Molecular weight: 12268.99 Da        Isoelectric Point: 3.9823

>T289972 WP_026786450.1 NZ_LR882944:c1809758-1809423 [Planktothrix agardhii]
MNFWIDAQLPPSLANWLVETFNVNATAIRDLGLRDAEDIEIFNAARNPGTVIVSKDSDFVELVTRLGTPPQILWLTCGNV
TNRNLRLILSNTFAEALPMLEAGEAIVEISD

Download         Length: 336 bp


Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8535.94 Da        Isoelectric Point: 6.2230

>AT289972 WP_026786451.1 NZ_LR882944:c1809985-1809755 [Planktothrix agardhii]
MTAKSLLNRITYNPRQCGGRPCIRGMRIRVSDILEMLAENVSSGEILEDFPDLEAEDIQACLLFAARRTNIPKLTV

Download         Length: 231 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A1J1JI02


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1J1JJG5

References