Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 3540974..3541451 Replicon chromosome
Accession NZ_LR882938
Organism Planktothrix agardhii strain No.2A

Toxin (Protein)


Gene name - Uniprot ID A0A1J1JEC9
Locus tag NMG72_RS15805 Protein ID WP_042155864.1
Coordinates 3541179..3541451 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1J1JHM1
Locus tag NMG72_RS15800 Protein ID WP_042155865.1
Coordinates 3540974..3541198 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMG72_RS15765 (NO2A_03164) 3536327..3536803 - 477 WP_042155870.1 R3H domain-containing nucleic acid-binding protein -
NMG72_RS15770 (NO2A_03165) 3536806..3537963 - 1158 WP_042155869.1 membrane protein insertase YidC -
NMG72_RS15775 (NO2A_03166) 3538109..3538501 - 393 WP_227364941.1 PH domain-containing protein -
NMG72_RS15780 (NO2A_03167) 3538473..3538877 - 405 WP_042155868.1 ribonuclease P protein component -
NMG72_RS15785 (NO2A_03168) 3538987..3539124 - 138 WP_071783091.1 50S ribosomal protein L34 -
NMG72_RS15790 (NO2A_03169) 3539241..3539750 - 510 WP_026797999.1 DUF2808 domain-containing protein -
NMG72_RS15795 (NO2A_03170) 3539898..3540542 - 645 WP_042155867.1 Uma2 family endonuclease -
NMG72_RS15800 (NO2A_03171) 3540974..3541198 - 225 WP_042155865.1 CopG family antitoxin Antitoxin
NMG72_RS15805 (NO2A_03172) 3541179..3541451 - 273 WP_042155864.1 BrnT family toxin Toxin
NMG72_RS15810 (NO2A_03174) 3542232..3544322 + 2091 WP_227381269.1 DUF4352 domain-containing protein -
NMG72_RS15815 3544713..3544931 - 219 Protein_3116 IS701 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin

CopG antitoxin

(3-68)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10918.26 Da        Isoelectric Point: 7.2018

>T289968 WP_042155864.1 NZ_LR882938:c3541451-3541179 [Planktothrix agardhii]
MYSFEYDDNKSRTNQQKHGIDFIEAQQLWQDDDLLEIQATSETESRFLAIGKLKQKHWTAVITYRLENIRIISVRRSRPN
EVIWYESRRI

Download         Length: 273 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8689.84 Da        Isoelectric Point: 4.4633

>AT289968 WP_042155865.1 NZ_LR882938:c3541198-3540974 [Planktothrix agardhii]
MKAEEFDAKFDTGEDLTEFMDFSTARRPNREKQKIELNLPLWMIRQLEAEAQKQGISPQTFLENYLAENLAPVR

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J1JEC9

Antitoxin

Source ID Structure
AlphaFold DB A0A1J1JHM1

References