Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 1810209..1811743 Replicon chromosome
Accession NC_020515
Organism Bibersteinia trehalosi USDA-ARS-USMARC-192

Toxin (Protein)


Gene name hipA Uniprot ID A0A4V7I8D4
Locus tag WQG_RS08200 Protein ID WP_015433059.1
Coordinates 1810209..1811495 (-) Length 429 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag WQG_RS08205 Protein ID WP_015433060.1
Coordinates 1811489..1811743 (-) Length 85 a.a.

Genomic Context

WQG_RS08170WQG_RS08195WQG_RS08215WQG_RS08220WQG_RS08225WQG_RS08230WQG_RS08175WQG_RS08180WQG_RS08185WQG_RS08190WQG_RS08200WQG_RS08205WQG_RS11425WQG_RS08210WQG_RS08235
Location: 1805228..1806376 (1149 bp)
Type: Others
Protein ID: WP_015433053.1
Location: 1809709..1810137 (429 bp)
Type: Others
Protein ID: WP_015433058.1
Location: 1812845..1814158 (1314 bp)
Type: Others
Protein ID: WP_015433063.1
Location: 1814392..1814844 (453 bp)
Type: Others
Protein ID: WP_025266848.1
Location: 1814848..1815477 (630 bp)
Type: Others
Protein ID: WP_015433065.1
Location: 1815470..1816051 (582 bp)
Type: Others
Protein ID: WP_015433066.1
Location: 1806442..1807116 (675 bp)
Type: Others
Protein ID: WP_038445703.1
Location: 1807164..1807739 (576 bp)
Type: Others
Protein ID: WP_015433055.1
Location: 1807779..1808558 (780 bp)
Type: Others
Protein ID: WP_015433056.1
Location: 1808559..1809560 (1002 bp)
Type: Others
Protein ID: WP_015433057.1
Location: 1810209..1811495 (1287 bp)
Type: Toxin
Protein ID: WP_015433059.1
Location: 1811489..1811743 (255 bp)
Type: Antitoxin
Protein ID: WP_015433060.1
Location: 1811859..1812044 (186 bp)
Type: Others
Protein ID: Protein_1585
Location: 1812182..1812586 (405 bp)
Type: Others
Protein ID: Protein_1586
Location: 1816102..1816743 (642 bp)
Type: Others
Protein ID: WP_015433067.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
WQG_RS081701805228..1806376+1149WP_015433053.1TIR domain-containing protein-
WQG_RS081751806442..1807116-675WP_038445703.1stress protein-
WQG_RS081801807164..1807739-576WP_015433055.1TerD family protein-
WQG_RS081851807779..1808558-780WP_015433056.1hypothetical protein-
WQG_RS081901808559..1809560-1002WP_015433057.1TerC/Alx family metal homeostasis membrane protein-
WQG_RS081951809709..1810137+429WP_015433058.1helix-turn-helix domain-containing protein-
WQG_RS082001810209..1811495-1287WP_015433059.1type II toxin-antitoxin system HipA family toxinToxin
WQG_RS082051811489..1811743-255WP_015433060.1helix-turn-helix domain-containing proteinAntitoxin
WQG_RS114251811859..1812044-186Protein_1585ATP-binding protein-
WQG_RS082101812182..1812586-405Protein_1586ABC transporter ATP-binding protein-
WQG_RS082151812845..1814158+1314WP_015433063.1MFS transporter-
WQG_RS082201814392..1814844+453WP_025266848.1hypothetical protein-
WQG_RS082251814848..1815477+630WP_015433065.1DsbA family oxidoreductase-
WQG_RS082301815470..1816051+582WP_015433066.1rhomboid family intramembrane serine protease-
WQG_RS082351816102..1816743-642WP_015433067.1orotate phosphoribosyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(148-394)

Antitoxin

Cro/C1-type helix-turn-helix domain

(10-64)


Sequences

Toxin        


Download         Length: 429 a.a.        Molecular weight: 48546.92 Da        Isoelectric Point: 7.9839

>T28989 WP_015433059.1 NC_020515:c1811495-1810209 [Bibersteinia trehalosi USDA-ARS-USMARC-192]
MVGNVLTVAMNGLEVGHWQKLSSGATEFCYIPSWLNSPRKRAISLSLPLSDQIYRGDVVYNFFDNLLPDNELIRSRIQQR
FQTTTKSPFDLLSAIGQDCVGAIQLYNQTPSPTQNINAQKLVDQEIEHILQNYQSLPLGMAEQADFRISIAGAQEKTAFL
YHQGEWKRPLGSTPTTHIFKLPIGVVGQGQIDLSNSCENEWLCLNILRVFGLPVSQAEIAYFGETKVLIIERFDRRWAKD
NSYLLRLPQEDMCQAFNIAPARKYENDGGVGILPIMQLLKGSSNALADQKAFFKAQILFWLLCAIDGHAKNFSLFLEPNN
RYKLTPFYDVISAYPLISPKGLQKQKVKMAMAWHGEQNKHYLWDKIQLRHIFNTAKLAGLSKQTVEEILQEIVVASSRLN
SIPTQHLPEQIVDPILSEMERKLVVVNR

Download         Length: 1287 bp

>T28989 NC_020515:c1811495-1810209 [Bibersteinia trehalosi USDA-ARS-USMARC-192]
ATGGTAGGCAATGTACTGACGGTTGCGATGAATGGGTTAGAAGTTGGGCATTGGCAAAAACTTTCTAGCGGAGCAACGGA
ATTTTGTTATATCCCGAGCTGGCTCAACTCTCCACGAAAACGAGCGATTTCTCTTTCATTACCGCTATCGGATCAAATTT
ATCGTGGTGATGTAGTCTATAATTTTTTCGATAATTTGTTGCCGGACAATGAATTAATTCGCTCCCGTATTCAGCAACGT
TTTCAAACCACCACAAAATCGCCGTTCGATTTGCTTTCGGCAATCGGGCAAGACTGTGTGGGAGCTATTCAGCTTTATAA
TCAAACACCTTCGCCCACTCAGAACATTAACGCTCAAAAGCTGGTAGATCAGGAAATTGAGCATATTTTACAAAATTATC
AAAGCCTGCCACTGGGTATGGCGGAGCAGGCAGATTTCCGTATTTCAATTGCTGGTGCGCAGGAAAAAACGGCCTTTCTT
TACCATCAAGGCGAATGGAAACGCCCGTTGGGTTCAACGCCAACCACACATATTTTCAAATTACCGATCGGTGTTGTTGG
ACAAGGGCAAATCGACCTTTCGAATAGTTGTGAAAATGAGTGGCTCTGTTTGAATATTTTGCGGGTATTTGGCTTGCCTG
TATCTCAGGCGGAAATTGCCTATTTTGGTGAAACCAAAGTGCTGATTATCGAACGTTTTGACCGCCGTTGGGCGAAGGAC
AATAGCTATTTGCTCCGTTTACCACAAGAAGATATGTGCCAAGCGTTTAACATTGCTCCGGCTCGGAAATATGAAAATGA
TGGTGGCGTTGGTATTCTGCCAATTATGCAACTCCTCAAAGGTTCGAGCAATGCACTTGCCGATCAAAAAGCCTTTTTCA
AAGCCCAAATTCTGTTTTGGCTGCTCTGTGCAATTGACGGACACGCCAAAAATTTCAGCCTATTTTTAGAACCTAACAAC
CGCTATAAACTTACGCCGTTTTACGATGTGATTTCCGCCTACCCATTGATTAGCCCGAAAGGCTTGCAAAAACAGAAAGT
TAAAATGGCAATGGCGTGGCACGGCGAGCAGAATAAGCACTATCTTTGGGATAAAATCCAACTTCGACATATTTTTAATA
CTGCAAAGTTAGCAGGCTTATCAAAACAGACAGTGGAGGAAATATTACAGGAGATTGTTGTGGCTTCATCACGATTAAAT
AGTATCCCGACACAACATTTGCCCGAACAAATTGTTGACCCGATTTTGAGTGAGATGGAGAGAAAGTTGGTTGTGGTGAA
TAGGTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9528.92 Da        Isoelectric Point: 4.7661

>AT28989 WP_015433060.1 NC_020515:c1811743-1811489 [Bibersteinia trehalosi USDA-ARS-USMARC-192]
MVATTPQMLAHAVKEYRNLQKKSQTEVATVANTKQSTISIFENDPTGTKIETLFNILMALELELVVQPRPKSRDILQDEE
GEIW

Download         Length: 255 bp

>AT28989 NC_020515:c1811743-1811489 [Bibersteinia trehalosi USDA-ARS-USMARC-192]
ATGGTTGCTACCACGCCACAAATGTTGGCACACGCAGTGAAAGAATACCGTAACTTACAGAAAAAATCGCAAACTGAAGT
TGCCACAGTTGCTAACACTAAGCAATCGACGATCTCCATATTTGAAAATGATCCCACTGGCACAAAAATTGAAACTTTGT
TCAATATTTTAATGGCATTAGAATTAGAGTTAGTCGTCCAGCCTCGCCCGAAAAGTCGTGATATTTTGCAAGATGAAGAG
GGCGAGATATGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A4V7I8D4

Antitoxin

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Source
ID
Structure
No matching records found

References