Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) paaR-paaA-parE/-
Location 1606044..1606396 Replicon chromosome
Accession NC_020301
Organism Bartonella vinsonii subsp. berkhoffii str. Winnie

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag BVWIN_RS08825 Protein ID WP_144050574.1
Coordinates 1606235..1606396 (+) Length 54 a.a.

Antitoxin (Protein)


Gene name paaA Uniprot ID -
Locus tag BVWIN_RS07290 Protein ID WP_041578546.1
Coordinates 1606044..1606235 (+) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BVWIN_RS07265 1601440..1601799 + 360 WP_010705783.1 helix-turn-helix domain-containing protein -
BVWIN_RS07270 1601907..1602425 - 519 WP_010705784.1 DUF1465 family protein -
BVWIN_RS07275 1602591..1603736 - 1146 WP_015399375.1 OpgC domain-containing protein -
BVWIN_RS07280 1603849..1604559 + 711 WP_015399376.1 thiamine phosphate synthase -
BVWIN_RS07285 1605380..1605700 + 321 WP_015399377.1 hypothetical protein -
BVWIN_RS07290 1606044..1606235 + 192 WP_041578546.1 hypothetical protein Antitoxin
BVWIN_RS08825 1606235..1606396 + 162 WP_144050574.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BVWIN_RS08830 1606401..1606523 + 123 WP_210160690.1 type II toxin-antitoxin system RelE/ParE family toxin -
BVWIN_RS07295 1606843..1607199 + 357 WP_010705789.1 helix-turn-helix domain-containing protein -
BVWIN_RS07300 1607345..1608397 + 1053 WP_010705790.1 sel1 repeat family protein -
BVWIN_RS07305 1608574..1608941 + 368 Protein_1359 helix-turn-helix transcriptional regulator -
BVWIN_RS08795 1609260..1609436 + 177 WP_155806780.1 hypothetical protein -
BVWIN_RS07310 1609575..1609973 + 399 WP_010705792.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-41)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 54 a.a.        Molecular weight: 5929.10 Da        Isoelectric Point: 10.1074

>T28974 WP_144050574.1 NC_020301:1606235-1606396 [Bartonella vinsonii subsp. berkhoffii str. Winnie]
MLPVVWLPSARDDLPQILTYIAQENPPAAARRMKKLLEACVLPFRTSVPVSPK

Download         Length: 162 bp

>T28974 NC_020301:1606235-1606396 [Bartonella vinsonii subsp. berkhoffii str. Winnie]
ATGCTACCAGTTGTCTGGTTGCCTTCGGCGCGCGATGATTTACCTCAAATTTTAACTTACATTGCGCAGGAAAATCCGCC
TGCTGCTGCACGGCGAATGAAAAAACTTCTGGAAGCTTGTGTCCTACCATTCCGAACATCCGTACCTGTATCGCCAAAAT
GA

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7362.29 Da        Isoelectric Point: 4.1168

>AT28974 WP_041578546.1 NC_020301:1606044-1606235 [Bartonella vinsonii subsp. berkhoffii str. Winnie]
MKSTLSPFFSEFETIEQENSYTTWLREKAAMSLANPYPTLAHDEVMAEMETIIEQLEAEQKKF

Download         Length: 192 bp

>AT28974 NC_020301:1606044-1606235 [Bartonella vinsonii subsp. berkhoffii str. Winnie]
ATGAAAAGTACCCTTTCTCCGTTCTTCTCAGAGTTTGAAACCATTGAACAGGAAAACAGCTATACTACGTGGCTCCGTGA
AAAAGCAGCAATGAGCCTTGCAAATCCATATCCTACACTTGCGCATGATGAAGTTATGGCTGAAATGGAAACTATCATAG
AACAACTTGAAGCTGAACAGAAGAAATTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References