Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | V | Classification (family/domain) | ghoTS/ghoT-GhoS |
Location | 4351027..4351524 | Replicon | chromosome |
Accession | NZ_LR882493 | ||
Organism | Escherichia coli isolate 2016-17-292 |
Toxin (Protein)
Gene name | ghoT | Uniprot ID | L4JJG6 |
Locus tag | IHO92_RS21335 | Protein ID | WP_001173343.1 |
Coordinates | 4351027..4351200 (-) | Length | 58 a.a. |
Antitoxin (Protein)
Gene name | ghoS | Uniprot ID | J7RC38 |
Locus tag | IHO92_RS21340 | Protein ID | WP_001425728.1 |
Coordinates | 4351228..4351524 (-) | Length | 99 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IHO92_RS21325 | 4347697..4349154 | + | 1458 | WP_000856841.1 | dipeptide/tripeptide permease DtpC | - |
IHO92_RS21330 | 4349391..4350908 | + | 1518 | WP_001295074.1 | lysine--tRNA ligase | - |
IHO92_RS21335 | 4351027..4351200 | - | 174 | WP_001173343.1 | type V toxin-antitoxin system toxin GhoT | Toxin |
IHO92_RS21340 | 4351228..4351524 | - | 297 | WP_001425728.1 | type V toxin-antitoxin system endoribonuclease antitoxin GhoS | Antitoxin |
IHO92_RS21345 | 4351751..4352023 | - | 273 | WP_000405647.1 | N-acetyltransferase | - |
IHO92_RS21350 | 4352035..4352265 | - | 231 | WP_000371700.1 | (4Fe-4S)-binding protein | - |
IHO92_RS21355 | 4352446..4354077 | + | 1632 | WP_001216487.1 | sensor histidine kinase | - |
IHO92_RS21360 | 4354074..4354793 | + | 720 | WP_000611288.1 | two-component system response regulator DcuR | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QI41 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | J7RC38 |