Detailed information of TA system TA028961

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-YefM
• Location: 2083094..2083479
• Replicon: chromosome
• Accession: NC_020286
• Organism: Synechocystis sp. PCC 6803

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: MYO_RS18780
• Protein ID: WP_080504056.1
• Coordinates: 2083375..2083479 (+)
• Length: 35 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: MYO_RS09900
• Protein ID: WP_010873096.1
• Coordinates: 2083094..2083378 (+)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MYO_RS09865	2078153..2079988	+	1836	WP_010873091.1	hypothetical protein	-
MYO_RS09870	2080132..2081184	-	1053	WP_010873092.1	2OG-Fe(II) oxygenase	-
MYO_RS09875	2081411..2081638	+	228	WP_020862282.1	DUF2281 domain-containing protein	-
MYO_RS18775	2081684..2082028	+	345	WP_071822655.1	type II toxin-antitoxin system VapC family toxin	-
MYO_RS09885	2082190..2082474	+	285	WP_014407120.1	BrnT family toxin	-
MYO_RS09890	2082479..2082685	+	207	WP_010873094.1	hypothetical protein	-
MYO_RS09895	2082713..2082952	+	240	WP_010873095.1	hypothetical protein	-
MYO_RS09900	2083094..2083378	+	285	WP_010873096.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
MYO_RS18780	2083375..2083479	+	105	WP_080504056.1	type II toxin-antitoxin system YoeB family toxin	Toxin
MYO_RS09905	2083573..2084397	-	825	WP_010873097.1	photosystem II manganese-stabilizing polypeptide	-
MYO_RS09910	2084624..2085001	+	378	WP_010873098.1	hypothetical protein	-
MYO_RS09920	2085398..2085760	-	363	WP_010873099.1	hypothetical protein	-
MYO_RS09925	2085948..2087291	+	1344	WP_010873100.1	3-phosphoshikimate 1-carboxyvinyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-32)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (19-83)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 4196.90 Da
• Isoelectric Point: 8.5633

>T28961 WP_080504056.1 NC_020286:2083375-2083479 [Synechocystis sp. PCC 6803]
VKLIFSEQAWSDYLYWQQNDKKILKRINTLVELI

Nucleotide

• Length: 105 bp

>T28961 NC_020286:2083375-2083479 [Synechocystis sp. PCC 6803]
GTGAAGCTAATTTTCTCTGAGCAAGCCTGGAGCGATTATCTTTACTGGCAACAAAACGACAAGAAAATACTTAAAAGAAT
CAATACCTTAGTTGAATTAATTTGA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10540.02 Da
• Isoelectric Point: 4.1364

>AT28961 WP_010873096.1 NC_020286:2083094-2083378 [Synechocystis sp. PCC 6803]
MGETLPQQLPNMNAVSQIIAQQKLAAIMEQVCSDHVPTIITRDTQPSVVMISLEDYQSLEETAYLLRSPNNAQKLMSAIK
QLENDQGVERELLE

Nucleotide

• Length: 285 bp

>AT28961 NC_020286:2083094-2083378 [Synechocystis sp. PCC 6803]
ATGGGGGAAACTTTGCCCCAACAATTGCCAAACATGAACGCAGTCAGCCAAATTATTGCACAACAAAAACTTGCAGCTAT
CATGGAGCAAGTATGTAGTGATCATGTTCCAACAATTATCACCAGGGATACCCAACCATCTGTCGTCATGATTTCCCTGG
AAGACTATCAGTCATTAGAAGAAACAGCATATCTACTACGTAGCCCGAACAATGCTCAAAAATTGATGTCGGCGATCAAG
CAATTAGAAAATGATCAAGGTGTCGAAAGGGAACTATTGGAGTGA