Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 544531..545090 Replicon chromosome
Accession NC_020286
Organism Synechocystis sp. PCC 6803

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MYO_RS02535 Protein ID WP_010871694.1
Coordinates 544752..545090 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MYO_RS02530 Protein ID WP_010871693.1
Coordinates 544531..544755 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MYO_RS02505 539564..540265 + 702 WP_071822669.1 HAD family hydrolase -
MYO_RS02510 540365..541567 + 1203 WP_010871689.1 class I SAM-dependent methyltransferase -
MYO_RS02515 541607..542098 - 492 WP_010871690.1 hypothetical protein -
MYO_RS02520 542305..542844 + 540 WP_010871691.1 tellurium resistance TerZ family protein -
MYO_RS02525 542970..544373 - 1404 WP_010871692.1 glutamate decarboxylase -
MYO_RS02530 544531..544755 + 225 WP_010871693.1 DUF433 domain-containing protein Antitoxin
MYO_RS02535 544752..545090 + 339 WP_010871694.1 DUF5615 family PIN-like protein Toxin
MYO_RS02540 545093..546058 - 966 WP_010871695.1 carbon-nitrogen hydrolase family protein -
MYO_RS02545 546055..546867 - 813 WP_014407074.1 urease accessory protein UreD -
MYO_RS02550 546927..547376 - 450 WP_010871697.1 photosystem II protein PsbQ -
MYO_RS02555 547738..548634 + 897 WP_010871698.1 prohibitin family protein -
MYO_RS02560 548631..549203 - 573 WP_010871699.1 gamma carbonic anhydrase family protein -
MYO_RS02565 549496..549831 + 336 WP_010871700.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12464.32 Da        Isoelectric Point: 4.2931

>T28958 WP_010871694.1 NC_020286:544752-545090 [Synechocystis sp. PCC 6803]
MNIWVDAQLPPTLADWLSSNFDLEASALRDLGLRDARDIEIFDAARVANSVIMTKDSDFVDLVCRLGIPPQIIWLTCGNV
TNRNLRRILSSTLPQALEKLQAGEIIIEISNS

Download         Length: 339 bp

>T28958 NC_020286:544752-545090 [Synechocystis sp. PCC 6803]
ATGAATATTTGGGTTGATGCTCAACTACCTCCAACATTGGCAGATTGGCTGTCGAGTAATTTTGATTTAGAGGCGTCAGC
TTTGAGGGATCTGGGATTACGGGATGCAAGAGACATTGAAATTTTTGATGCCGCACGAGTTGCCAACTCTGTAATCATGA
CAAAAGACAGCGACTTCGTTGATCTTGTATGTCGATTAGGAATACCACCTCAAATCATTTGGCTAACTTGCGGTAACGTT
ACGAATCGAAACTTACGTCGAATTCTCTCAAGTACTTTGCCACAGGCTCTGGAAAAACTGCAAGCAGGCGAAATTATCAT
AGAAATCAGCAACTCCTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8232.51 Da        Isoelectric Point: 4.6320

>AT28958 WP_010871693.1 NC_020286:544531-544755 [Synechocystis sp. PCC 6803]
MNSLLSRITQTPGQCGGRPCIRGMRIRVSDILEMLAENVSTSEILEDFPDLEMADIQACLVFAARRTDFSRLTA

Download         Length: 225 bp

>AT28958 NC_020286:544531-544755 [Synechocystis sp. PCC 6803]
ATGAATAGCTTACTGTCTCGCATTACCCAAACCCCCGGTCAGTGTGGTGGTCGTCCTTGTATTCGAGGGATGAGGATTCG
AGTGAGCGACATCCTAGAAATGTTAGCTGAGAATGTTAGCACCTCTGAGATTTTAGAGGACTTTCCAGACCTAGAAATGG
CCGATATTCAGGCTTGTCTAGTGTTTGCTGCACGGCGGACTGATTTTTCCCGGTTGACGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References