Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012613..2012884 Replicon chromosome
Accession NZ_LR881940
Organism Escherichia coli isolate 2015-01-2097

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012743..2012846 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012613..2012884 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHP11_RS09630 2009168..2009830 - 663 WP_000944256.1 exodeoxyribonuclease X -
IHP11_RS09635 2009854..2010510 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
IHP11_RS09640 2010612..2010842 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IHP11_RS09645 2010981..2011355 + 375 WP_000255065.1 CopC domain-containing protein YobA -
IHP11_RS09650 2011359..2012231 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
IHP11_RS09655 2012244..2012585 + 342 WP_000976472.1 YebY family protein -
- 2012613..2012884 - 272 - - Antitoxin
- 2012743..2012846 + 104 - - Toxin
IHP11_RS09660 2012981..2013616 + 636 WP_191521789.1 protein-serine/threonine phosphatase -
IHP11_RS09665 2013637..2013828 - 192 WP_001338167.1 YebW family protein -
IHP11_RS09670 2013933..2014169 - 237 WP_001338166.1 DUF1480 family protein -
IHP11_RS09675 2014287..2015726 - 1440 WP_001338165.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1938322..2015732 77410


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T289542 NZ_LR881940:2012743-2012846 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT289542 NZ_LR881940:c2012884-2012613 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References