Detailed information of TA system TA028952

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yxiD-yxxD/-
• Location: 441288..442076
• Replicon: chromosome
• Accession: NC_020272
• Organism: Bacillus amyloliquefaciens IT-45

Toxin (Protein)

• Gene name: yxiD
• Uniprot ID: -
• Locus tag: KSO_RS19980
• Protein ID: WP_079891856.1
• Coordinates: 441288..441629 (+)
• Length: 114 a.a.

Antitoxin (Protein)

• Gene name: yxxD
• Uniprot ID: -
• Locus tag: KSO_RS02280
• Protein ID: WP_015387595.1
• Coordinates: 441639..442076 (+)
• Length: 146 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KSO_RS02250	436462..438207	+	1746	WP_015387593.1	ribonuclease YeeF family protein	-
KSO_RS02255	438224..438529	+	306	WP_003151282.1	hypothetical protein	-
KSO_RS20195	438700..439225	+	526	Protein_449	HNH endonuclease	-
KSO_RS19325	439227..439692	+	466	Protein_450	DUF2004 domain-containing protein	-
KSO_RS19975	440331..440669	+	339	Protein_451	transposase	-
KSO_RS19980	441288..441629	+	342	WP_079891856.1	HNH endonuclease	Toxin
KSO_RS02280	441639..442076	+	438	WP_015387595.1	SMI1/KNR4 family protein	Antitoxin
KSO_RS02285	442247..442687	+	441	Protein_454	SMI1/KNR4 family protein	-
KSO_RS02290	442879..443379	+	501	WP_015387596.1	hypothetical protein	-
KSO_RS02295	443419..444135	+	717	WP_015387597.1	endonuclease V	-
KSO_RS02300	444222..445103	-	882	WP_015387598.1	LysR family transcriptional regulator	-
KSO_RS02305	445226..445771	+	546	WP_015387599.1	flavodoxin family protein	-
KSO_RS02310	445768..445986	+	219	WP_015387600.1	hypothetical protein	-
KSO_RS02315	446013..446549	-	537	WP_014305969.1	chromate resistance efflux protein ChrA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 13224.74 Da
• Isoelectric Point: 9.6942

>T28952 WP_079891856.1 NC_020272:441288-441629 [Bacillus amyloliquefaciens IT-45]
IKEALRNNNYEKLTPKETAKHRSKFTSSLKDRLIAEWEEKTNQKWPRYTEEVFDKHGEVARSIGQPYDAHHIIENNFGGP
HEWWNIHPAKYPDEHQAGIHGKGAPSGKLFPRR

Nucleotide

• Length: 342 bp

>T28952 NC_020272:441288-441629 [Bacillus amyloliquefaciens IT-45]
ATAAAAGAAGCTTTAAGAAATAATAACTATGAGAAATTAACACCAAAAGAAACAGCTAAGCATAGGAGCAAATTCACATC
AAGTTTGAAAGATAGATTGATTGCAGAATGGGAAGAAAAAACCAATCAAAAGTGGCCTAGATATACAGAAGAGGTTTTTG
ATAAGCATGGAGAAGTTGCCCGAAGTATTGGTCAACCGTACGATGCCCATCATATCATCGAGAACAACTTTGGTGGCCCT
CACGAATGGTGGAATATTCATCCGGCAAAATATCCGGATGAACACCAAGCGGGTATACATGGAAAGGGAGCACCATCAGG
AAAACTTTTTCCAAGGAGGTAA

Antitoxin

Protein

• Length: 146 a.a.
• Molecular weight: 16992.02 Da
• Isoelectric Point: 3.8929

>AT28952 WP_015387595.1 NC_020272:441639-442076 [Bacillus amyloliquefaciens IT-45]
MAEFEFINHLENKTYKVPEEDILKAEQRMNVDIPNDLKQLYLEVGYGFIKGESDNAINRILGPGAVADIRLREGIFEFDP
DLGELYDDENKLIFFEVNEGVYISIDLRLANNPIFYFDTQIAESLEDFFKKFLNDNEYYIDLIED

Nucleotide

• Length: 438 bp

>AT28952 NC_020272:441639-442076 [Bacillus amyloliquefaciens IT-45]
ATGGCTGAATTTGAATTTATAAATCATTTAGAAAATAAAACATATAAGGTACCTGAAGAGGATATATTAAAAGCTGAACA
AAGAATGAACGTAGATATTCCAAATGATTTAAAACAATTATATTTAGAAGTCGGTTATGGTTTTATTAAAGGTGAAAGTG
ATAATGCAATTAATAGGATATTGGGGCCAGGGGCAGTAGCCGACATTAGACTAAGAGAAGGAATTTTTGAGTTTGACCCA
GATTTAGGTGAACTTTATGATGATGAAAATAAACTTATTTTTTTTGAAGTAAACGAGGGTGTTTATATTTCTATAGATTT
ACGATTGGCAAATAATCCAATATTTTATTTTGACACTCAAATAGCTGAATCTTTAGAGGATTTTTTTAAAAAGTTCCTCA
ATGATAATGAATATTATATTGATTTAATTGAGGATTAG