Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1907335..1907606 Replicon chromosome
Accession NZ_LR881938
Organism Escherichia coli str. K-12 substr. MG1655 strain K-12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1907373..1907476 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1907335..1907606 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IEU92_RS09355 1904492..1905931 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
IEU92_RS09360 1906049..1906285 + 237 WP_001295499.1 DUF1480 family protein -
IEU92_RS09365 1906390..1906581 + 192 WP_000457842.1 YebW family protein -
IEU92_RS09370 1906582..1907238 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1907335..1907606 + 272 - - Antitoxin
- 1907373..1907476 - 104 - - Toxin
IEU92_RS09375 1907634..1907975 - 342 WP_000976476.1 YebY family protein -
IEU92_RS09380 1907988..1908860 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
IEU92_RS09385 1908864..1909238 - 375 WP_000168747.1 CopC domain-containing protein YobA -
IEU92_RS09390 1909377..1909607 + 231 WP_000916763.1 DNA polymerase III subunit theta -
IEU92_RS09395 1909709..1910365 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
IEU92_RS09400 1910389..1911051 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T289515 NZ_LR881938:c1907476-1907373 [Escherichia coli str. K-12 substr. MG1655]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT289515 NZ_LR881938:1907335-1907606 [Escherichia coli str. K-12 substr. MG1655]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References