Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 74326..75045 Replicon chromosome
Accession NZ_LR881934
Organism Citrobacter freundii strain PSV

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag CITRO_RS00355 Protein ID WP_202580912.1
Coordinates 74326..74646 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag CITRO_RS00360 Protein ID WP_149382491.1
Coordinates 74698..75045 (-) Length 116 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CITRO_RS00330 70582..70955 - 374 Protein_65 hypothetical protein -
CITRO_RS00335 71361..71537 - 177 WP_003844487.1 hypothetical protein -
CITRO_RS00340 71655..71945 - 291 WP_044700468.1 SymE family type I addiction module toxin -
CITRO_RS00345 72072..72263 + 192 WP_032937148.1 toxin-antitoxin system HicB family antitoxin -
CITRO_RS00350 72278..74077 - 1800 WP_198682976.1 hypothetical protein -
CITRO_RS00355 74326..74646 - 321 WP_202580912.1 TA system toxin CbtA family protein Toxin
CITRO_RS00360 74698..75045 - 348 WP_149382491.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
CITRO_RS00365 75077..75298 - 222 WP_202580913.1 DUF987 domain-containing protein -
CITRO_RS00370 75307..75777 - 471 WP_202580914.1 DNA repair protein RadC -
CITRO_RS00375 75847..76668 - 822 WP_202580915.1 DUF945 domain-containing protein -
CITRO_RS00380 76743..77171 - 429 WP_202580916.1 hypothetical protein -
CITRO_RS00385 77207..77386 - 180 WP_105739593.1 hypothetical protein -
CITRO_RS00390 77437..78240 - 804 WP_202580917.1 hypothetical protein -
CITRO_RS00395 78260..78694 - 435 WP_202580918.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-104)

Antitoxin

Antitoxin CbeA

(18-115)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12169.84 Da        Isoelectric Point: 5.9559

>T289473 WP_202580912.1 NZ_LR881934:c74646-74326 [Citrobacter freundii]
MHIPTVPATVTVSSRLSPVQIWQKLLTYLLEHHYGLTINDTPFSNDTAILEHIEAGVNLTDAVNFLVERFELVRIDQKGF
SWQDQEPWITSLDVHRAQFNLGLKRS

Download         Length: 321 bp

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 12907.51 Da        Isoelectric Point: 6.0606

>AT289473 WP_149382491.1 NZ_LR881934:c75045-74698 [Citrobacter freundii]
MQSTTLSDTSAENASCFQWGLKRNITPCFGARLVQEGNRLYFLADRAGFNGSFSDDEALRLDQAFPLMMKQLERMLTTGE
LDPRSQHCVTRHHNGLTCEADTLGSHGYVYIAIYP

Download         Length: 348 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References