Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 80991..81616 | Replicon | plasmid 2_Linear- |
| Accession | NZ_LR881464 | ||
| Organism | Salmonella enterica subsp. enterica serovar Typhimurium isolate S.Tm LT2p22_assembled | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | STMLT2P22_RS24280 | Protein ID | WP_000911322.1 |
| Coordinates | 81218..81616 (+) | Length | 133 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | STMLT2P22_RS24275 | Protein ID | WP_000450265.1 |
| Coordinates | 80991..81218 (+) | Length | 76 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| STMLT2P22_RS24275 | 80991..81218 | + | 228 | WP_000450265.1 | toxin-antitoxin system antitoxin VapB | Antitoxin |
| STMLT2P22_RS24280 | 81218..81616 | + | 399 | WP_000911322.1 | tRNA(fMet)-specific endonuclease VapC | Toxin |
| STMLT2P22_RS24285 | 81625..83868 | - | 2244 | WP_000009320.1 | type IV conjugative transfer system coupling protein TraD | - |
| STMLT2P22_RS24290 | 84245..84976 | - | 732 | WP_000782438.1 | complement resistance protein TraT | - |
| STMLT2P22_RS24295 | 85012..85506 | - | 495 | WP_010999946.1 | entry exclusion protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..93927 | 93927 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 133 a.a. Molecular weight: 17065.17 Da Isoelectric Point: 12.9205
>T289471 WP_000911322.1 NZ_LR881464:81218-81616 [Salmonella enterica subsp. enterica serovar Typhimurium]
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Download Length: 399 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|