Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 80991..81616 Replicon plasmid 2_Linear-
Accession NZ_LR881464
Organism Salmonella enterica subsp. enterica serovar Typhimurium isolate S.Tm LT2p22_assembled

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag STMLT2P22_RS24280 Protein ID WP_000911322.1
Coordinates 81218..81616 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag STMLT2P22_RS24275 Protein ID WP_000450265.1
Coordinates 80991..81218 (+) Length 76 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
STMLT2P22_RS24275 80991..81218 + 228 WP_000450265.1 toxin-antitoxin system antitoxin VapB Antitoxin
STMLT2P22_RS24280 81218..81616 + 399 WP_000911322.1 tRNA(fMet)-specific endonuclease VapC Toxin
STMLT2P22_RS24285 81625..83868 - 2244 WP_000009320.1 type IV conjugative transfer system coupling protein TraD -
STMLT2P22_RS24290 84245..84976 - 732 WP_000782438.1 complement resistance protein TraT -
STMLT2P22_RS24295 85012..85506 - 495 WP_010999946.1 entry exclusion protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..93927 93927


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 133 a.a.        Molecular weight: 17065.17 Da        Isoelectric Point: 12.9205

>T289471 WP_000911322.1 NZ_LR881464:81218-81616 [Salmonella enterica subsp. enterica serovar Typhimurium]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 399 bp


Antitoxin


Download         Length: 76 a.a.        Molecular weight: 9759.25 Da        Isoelectric Point: 12.6750

>AT289471 WP_000450265.1 NZ_LR881464:80991-81218 [Salmonella enterica subsp. enterica serovar Typhimurium]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 228 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References