289467

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-YefM
Location 359066..359586 Replicon chromosome
Accession NZ_LR880474
Organism Microbacterium sp. Nx66 isolate Microbacterium sp. Nx66

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MICNX66_RS01640 Protein ID WP_187663053.1
Coordinates 359323..359586 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MICNX66_RS01635 Protein ID WP_085604709.1
Coordinates 359066..359326 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MICNX66_RS01620 354381..355787 + 1407 WP_187663051.1 PLP-dependent aminotransferase family protein -
MICNX66_RS01625 355797..357869 - 2073 WP_187664079.1 APC family permease -
MICNX66_RS01630 357971..359032 + 1062 WP_187663052.1 VanZ family protein -
MICNX66_RS01635 359066..359326 + 261 WP_085604709.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MICNX66_RS01640 359323..359586 + 264 WP_187663053.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MICNX66_RS01645 359640..360344 + 705 WP_187663054.1 GTP pyrophosphokinase family protein -
MICNX66_RS01650 360355..361677 - 1323 WP_187663055.1 amidohydrolase -
MICNX66_RS01655 361700..362344 - 645 WP_187663056.1 TetR/AcrR family transcriptional regulator -
MICNX66_RS01660 362497..364161 + 1665 WP_187663057.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(6-66)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10241.84 Da        Isoelectric Point: 10.7604

>T289467 WP_187663053.1 NZ_LR880474:359323-359586 [Microbacterium sp. Nx66]
VTRYRVEFTTAAAKEVRKLDPPLRRRILAGISDLEREPRPHGVRKLAGFDNAWRVRIGDYRVLYEVVDERVLVTVVRVAH
RRDVYDL

Download         Length: 264 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9018.08 Da        Isoelectric Point: 4.2682

>AT289467 WP_085604709.1 NZ_LR880474:359066-359326 [Microbacterium sp. Nx66]
MNTLSRSVPSKDLRDQLADVLGGVAYGAERVGVTRHGKLTAVVIGVDDLELLEELEAARDAAEFGAAKAADDGGRVSLDD
LRAELP

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References