Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1948965..1949199 Replicon chromosome
Accession NZ_LR878365
Organism Shigella flexneri 3a isolate 83

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1949095..1949198 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1948965..1949199 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMV05_RS09720 1945520..1946182 - 663 WP_000944269.1 exodeoxyribonuclease X -
JMV05_RS09725 1946206..1946862 - 657 WP_000011667.1 carbon-nitrogen hydrolase family protein YobB -
JMV05_RS09730 1946964..1947194 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JMV05_RS09735 1947333..1947707 + 375 WP_025758141.1 CopC domain-containing protein YobA -
JMV05_RS09740 1947711..1948583 + 873 Protein_1899 copper homeostasis membrane protein CopD -
JMV05_RS09745 1948596..1948937 + 342 WP_000976476.1 YebY family protein -
- 1948965..1949199 - 235 - - Antitoxin
- 1949095..1949198 + 104 - - Toxin
JMV05_RS09750 1949330..1950406 - 1077 WP_025758140.1 phage integrase Arm DNA-binding domain-containing protein -
JMV05_RS09755 1950372..1950653 - 282 WP_005127484.1 excisionase -
JMV05_RS09760 1950770..1951919 - 1150 Protein_1903 IS3 family transposase -
JMV05_RS09765 1951989..1952369 + 381 Protein_1904 IS66-like element accessory protein TnpA -
JMV05_RS09770 1952371..1952538 + 168 Protein_1905 phage tail protein -
JMV05_RS09775 1952489..1953112 + 624 WP_152030437.1 DUF4376 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T289446 NZ_LR878365:1949095-1949198 [Shigella flexneri 3a]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT289446 NZ_LR878365:c1949199-1948965 [Shigella flexneri 3a]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References