Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 4800541..4801208 Replicon chromosome
Accession NZ_LR861805
Organism Xanthomonas sp. CPBF 426 isolate

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag H7A87_RS20290 Protein ID WP_102582219.1
Coordinates 4800792..4801208 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag H7A87_RS20285 Protein ID WP_102582218.1
Coordinates 4800541..4800795 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7A87_RS20260 4795997..4796836 + 840 WP_119129942.1 SDR family oxidoreductase -
H7A87_RS20265 4796987..4798252 + 1266 WP_180496822.1 cardiolipin synthase B -
H7A87_RS20270 4798295..4798831 - 537 WP_119129943.1 hypothetical protein -
H7A87_RS20275 4799099..4799305 + 207 WP_119129944.1 hypothetical protein -
H7A87_RS20280 4799292..4800404 + 1113 WP_119129945.1 type II toxin-antitoxin system RelE/ParE family toxin -
H7A87_RS20285 4800541..4800795 + 255 WP_102582218.1 Arc family DNA-binding protein Antitoxin
H7A87_RS20290 4800792..4801208 + 417 WP_102582219.1 type II toxin-antitoxin system VapC family toxin Toxin
H7A87_RS20295 4801333..4801893 - 561 WP_104586335.1 hypothetical protein -
H7A87_RS20300 4802591..4804216 + 1626 WP_119129946.1 enterochelin esterase -
H7A87_RS20305 4804299..4804700 - 402 WP_126968946.1 DUF2384 domain-containing protein -
H7A87_RS20310 4805005..4805460 + 456 WP_180496823.1 hypothetical protein -
H7A87_RS20315 4805489..4805812 - 324 WP_119129948.1 hypothetical protein -
H7A87_RS20320 4805924..4806169 + 246 WP_115045825.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin

Arc-like DNA binding domain

(1-41)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14754.04 Da        Isoelectric Point: 5.6845

>T289437 WP_102582219.1 NZ_LR861805:4800792-4801208 [Xanthomonas sp. CPBF 426]
VILLDTNVISELWRPQPNPKVVAWIDAQAVETLFLSVVTVAELRFGIAVMPEGRKRSTLHARLESDVLPLFNGRLLAFDL
DASHAFATLASKARAAGLTLGRADAYIAATAAAQGLTVATRDTAPFAAMALDVIDPWS

Download         Length: 417 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9103.51 Da        Isoelectric Point: 10.7542

>AT289437 WP_102582218.1 NZ_LR861805:4800541-4800795 [Xanthomonas sp. CPBF 426]
MPSFTVRNIPDEVHRAIRARAALHGRSTEAEIRAILESAAKPADRVKLGSLLVDIGRDAGLTAKQADAFDTLRDKTAIKP
ISLK

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References