Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 2197421..2197926 Replicon chromosome
Accession NZ_LR828257
Organism Xanthomonas hortorum pv. vitians strain CFBP 498

Toxin (Protein)


Gene name relE Uniprot ID A0A6V7D3A5
Locus tag CFBP8129_RS09675 Protein ID WP_074056859.1
Coordinates 2197421..2197678 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID F0BZS9
Locus tag CFBP8129_RS09680 Protein ID WP_006448404.1
Coordinates 2197675..2197926 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP8129_RS09650 2193120..2194475 + 1356 WP_074056857.1 aminodeoxychorismate synthase component I -
CFBP8129_RS09655 2194491..2195600 + 1110 WP_074056858.1 endolytic transglycosylase MltG -
CFBP8129_RS09660 2195597..2196556 + 960 WP_180313645.1 DNA polymerase III subunit delta' -
CFBP8129_RS09665 2196553..2196906 + 354 WP_003483889.1 PilZ domain-containing protein -
CFBP8129_RS09675 2197421..2197678 - 258 WP_074056859.1 Txe/YoeB family addiction module toxin Toxin
CFBP8129_RS09680 2197675..2197926 - 252 WP_006448404.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CFBP8129_RS09685 2198112..2198438 + 327 WP_180313646.1 hypothetical protein -
CFBP8129_RS09690 2198681..2200300 - 1620 WP_174555969.1 propionate catabolism operon regulatory protein PrpR -
CFBP8129_RS09695 2200429..2201325 + 897 WP_074056861.1 methylisocitrate lyase -
CFBP8129_RS09700 2201401..2202555 + 1155 WP_074056862.1 2-methylcitrate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10156.66 Da        Isoelectric Point: 9.6587

>T289430 WP_074056859.1 NZ_LR828257:c2197678-2197421 [Xanthomonas hortorum pv. vitians]
VILQFADNAWEDYLYWQQTDKKMLKRINELIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKAENGILLIAQA
RYHYG

Download         Length: 258 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9255.48 Da        Isoelectric Point: 4.6536

>AT289430 WP_006448404.1 NZ_LR828257:c2197926-2197675 [Xanthomonas hortorum pv. vitians]
MDTITYSAARASLADTMDRVVNDHEPVIITRSGERAVVMVSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKERE
LAE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7D3A5

Antitoxin

Source ID Structure
AlphaFold DB A0A0G8MAJ7

References