Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4698436..4698801 Replicon chromosome
Accession NZ_LR828253
Organism Xanthomonas hortorum pv. gardneri strain CFBP 8129

Toxin (Protein)


Gene name EcnB Uniprot ID V7Z935
Locus tag CFBP498_RS20175 Protein ID WP_006451341.1
Coordinates 4698436..4698570 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag CFBP498_RS20180 Protein ID WP_006451340.1
Coordinates 4698649..4698801 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP498_RS20160 (CFBP8129_41140) 4695519..4696505 - 987 WP_228996049.1 MBL fold metallo-hydrolase -
CFBP498_RS20165 (CFBP8129_41150) 4696522..4697811 - 1290 WP_043909456.1 tryptophan--tRNA ligase -
CFBP498_RS20170 (CFBP8129_41160) 4697985..4698194 - 210 WP_006451342.1 CsbD family protein -
CFBP498_RS20175 (CFBP8129_41170) 4698436..4698570 - 135 WP_006451341.1 entericidin A/B family lipoprotein Toxin
CFBP498_RS20180 (CFBP8129_41180) 4698649..4698801 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
CFBP498_RS20185 (CFBP8129_41190) 4698911..4699834 - 924 WP_046931980.1 arginase -
CFBP498_RS20190 (CFBP8129_41200) 4700296..4700748 + 453 WP_006452080.1 roadblock/LC7 domain-containing protein -
CFBP498_RS20195 (CFBP8129_41210) 4700812..4701171 + 360 WP_006452081.1 hypothetical protein -
CFBP498_RS20200 (CFBP8129_41220) 4701263..4702180 + 918 WP_043910206.1 hypothetical protein -
CFBP498_RS20205 (CFBP8129_41230) 4702177..4702719 + 543 WP_006452083.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4493.34 Da        Isoelectric Point: 9.3487

>T289426 WP_006451341.1 NZ_LR828253:c4698570-4698436 [Xanthomonas hortorum pv. gardneri]
MKRAIMLLVLSVFSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT289426 WP_006451340.1 NZ_LR828253:c4698801-4698649 [Xanthomonas hortorum pv. gardneri]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7EZD1

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References