Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 3811213..3811718 Replicon chromosome
Accession NZ_LR828253
Organism Xanthomonas hortorum pv. gardneri strain CFBP 8129

Toxin (Protein)


Gene name relE Uniprot ID F0BZT0
Locus tag CFBP498_RS16055 Protein ID WP_006448405.1
Coordinates 3811461..3811718 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID F0BZS9
Locus tag CFBP498_RS16050 Protein ID WP_006448404.1
Coordinates 3811213..3811464 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP498_RS16030 (CFBP8129_32720) 3806584..3807738 - 1155 WP_006448400.1 2-methylcitrate synthase -
CFBP498_RS16035 (CFBP8129_32730) 3807814..3808710 - 897 WP_006448401.1 methylisocitrate lyase -
CFBP498_RS16040 (CFBP8129_32740) 3808857..3810458 + 1602 WP_006448402.1 propionate catabolism operon regulatory protein PrpR -
CFBP498_RS16045 (CFBP8129_32750) 3810701..3811027 - 327 WP_006448403.1 hypothetical protein -
CFBP498_RS16050 (CFBP8129_32760) 3811213..3811464 + 252 WP_006448404.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CFBP498_RS16055 (CFBP8129_32770) 3811461..3811718 + 258 WP_006448405.1 Txe/YoeB family addiction module toxin Toxin
CFBP498_RS16065 (CFBP8129_32790) 3812250..3812603 - 354 WP_003483889.1 PilZ domain-containing protein -
CFBP498_RS16070 (CFBP8129_32800) 3812600..3813559 - 960 WP_006448409.1 DNA polymerase III subunit delta' -
CFBP498_RS16075 (CFBP8129_32810) 3813556..3814608 - 1053 WP_228996226.1 endolytic transglycosylase MltG -
CFBP498_RS16080 (CFBP8129_32820) 3814681..3816036 - 1356 WP_006448411.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10200.71 Da        Isoelectric Point: 9.6587

>T289425 WP_006448405.1 NZ_LR828253:3811461-3811718 [Xanthomonas hortorum pv. gardneri]
VILQFADNTWEDYLYWQQTDKKMLKRINELIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKAENGILLIAQA
RYHYA

Download         Length: 258 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9255.48 Da        Isoelectric Point: 4.6536

>AT289425 WP_006448404.1 NZ_LR828253:3811213-3811464 [Xanthomonas hortorum pv. gardneri]
MDTITYSAARASLADTMDRVVNDHEPVIITRSGERAVVMVSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKERE
LAE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7E8S3

Antitoxin

Source ID Structure
AlphaFold DB A0A0G8MAJ7

References