Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 5725387..5727070 Replicon chromosome
Accession NZ_LR813084
Organism Delftia tsuruhatensis isolate BB1455

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag L1Z78_RS26080 Protein ID WP_234639224.1
Coordinates 5726216..5727070 (-) Length 285 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag L1Z78_RS26075 Protein ID WP_234639223.1
Coordinates 5725387..5726193 (-) Length 269 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1Z78_RS26055 (TML_05175) 5721176..5722048 - 873 WP_234639219.1 IclR family transcriptional regulator -
L1Z78_RS26060 (TML_05176) 5722061..5722831 - 771 WP_234639220.1 SDR family oxidoreductase -
L1Z78_RS26065 (TML_05178) 5723693..5724448 - 756 WP_234639221.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
L1Z78_RS26070 (TML_05179) 5724535..5725332 - 798 WP_234639222.1 aspartate dehydrogenase -
L1Z78_RS26075 (TML_05180) 5725387..5726193 - 807 WP_234639223.1 IclR family transcriptional regulator Antitoxin
L1Z78_RS26080 (TML_05181) 5726216..5727070 - 855 WP_234639224.1 alpha/beta fold hydrolase Toxin
L1Z78_RS26085 (TML_05182) 5727084..5727614 - 531 WP_016449821.1 cupin domain-containing protein -
L1Z78_RS26090 (TML_05183) 5727799..5728995 - 1197 WP_234639225.1 MFS transporter -
L1Z78_RS26095 (TML_05184) 5729018..5729902 - 885 WP_234639226.1 NAD(P)-dependent oxidoreductase -
L1Z78_RS26100 (TML_05185) 5730037..5730627 - 591 WP_234639227.1 TetR/AcrR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(43-270)

Antitoxin

Transcription regulator IclR, C-terminal

(137-255)


Sequences

Toxin        


Download         Length: 285 a.a.        Molecular weight: 29561.86 Da        Isoelectric Point: 8.2937

>T289377 WP_234639224.1 NZ_LR813084:c5727070-5726216 [Delftia tsuruhatensis]
MTAQTSSRMEQRLQAQFPEHLIALPGGAQVAWREAGDTASDFAVVMLHGISSGAASWLDVALALAPRTRVLAWDAPGYGR
STPLAPAAPTGADYARVLEQSLQALGVRRCLLVGHSLGALMGTPWAVQAGAGRVQQLVLISPAGGYGAPGMGEQQAKVRQ
GRLAALQEKGVEGLAAAIDQRLVSPSAPEPVRQWVRWNTARLHAAGYAQAVELLCRSDLGQAAGQLAMPVEVWVGAHDVV
TPPAACAAWAARLGARYVTLAAAGHASVVEQPADVAQRLATLLT

Download         Length: 855 bp

Antitoxin


Download         Length: 269 a.a.        Molecular weight: 29004.05 Da        Isoelectric Point: 5.3466

>AT289377 WP_234639223.1 NZ_LR813084:c5726193-5725387 [Delftia tsuruhatensis]
MSDTSETLSTDNDRYTVPALERGLRLLACFSPSQPVWSAPDLARTLALPRSTVFRMLTTLEGMGYLQRSGTEYRLGLAVL
RLGYDYLSTQPLAQLAEPVLQSLCERLGFTTNLALLDGTSVVYVARIAPAGAFQGAVRVGSRLPAHATVLGRALLQDMDA
DQLRALFGGSELPQFSESTPRSVEQLLQLLQQDHERGYAMGEGFYEPGVSSIAAPVRDAQGRIVAGLGMAVAFTEIAPGR
MADWVEQVRAAADELAGHLRAQHPGFLR

Download         Length: 807 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References