Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 872134..872714 Replicon chromosome
Accession NZ_LR813084
Organism Delftia tsuruhatensis isolate BB1455

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag L1Z78_RS03995 Protein ID WP_234640265.1
Coordinates 872134..872514 (-) Length 127 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A072THC0
Locus tag L1Z78_RS04000 Protein ID WP_016448366.1
Coordinates 872511..872714 (-) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1Z78_RS03975 (TML_00795) 867457..868698 + 1242 WP_234640261.1 ABC transporter substrate-binding protein -
L1Z78_RS03980 (TML_00796) 868695..869453 + 759 WP_234640262.1 ABC transporter permease -
L1Z78_RS03985 (TML_00797) 869488..871074 - 1587 WP_234640263.1 Ig-like domain repeat protein -
L1Z78_RS03990 (TML_00798) 871304..872056 + 753 WP_234640264.1 helix-turn-helix transcriptional regulator -
L1Z78_RS03995 (TML_00799) 872134..872514 - 381 WP_234640265.1 type II toxin-antitoxin system VapC family toxin Toxin
L1Z78_RS04000 (TML_00800) 872511..872714 - 204 WP_016448366.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
L1Z78_RS04005 (TML_00801) 872865..873677 + 813 WP_234640266.1 glucose 1-dehydrogenase -
L1Z78_RS04010 (TML_00802) 873795..875462 + 1668 WP_234640267.1 VRR-NUC domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-114)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 13833.26 Da        Isoelectric Point: 8.8276

>T289376 WP_234640265.1 NZ_LR813084:c872514-872134 [Delftia tsuruhatensis]
MNPVLVDTSVWIDHFRQGNPHLAQLLQQDMALMHPLVLGELACGTPPARARTLADLQRLKPARQASMREVLALIEREQLF
GLGCGLVDITLLASALMSSGASLWSRDKRLHALAQRFGIACRSVLP

Download         Length: 381 bp

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7499.60 Da        Isoelectric Point: 4.5702

>AT289376 WP_016448366.1 NZ_LR813084:c872714-872511 [Delftia tsuruhatensis]
MRTTVTIDDALYEEALELAEPEMDKADLFREAIKTFVRVQAAKRLAALGGSAPDMREIPRRPQGIEP

Download         Length: 204 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A072THC0

References