Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 110431..111073 Replicon chromosome
Accession NZ_LR813084
Organism Delftia tsuruhatensis isolate BB1455

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag L1Z78_RS00495 Protein ID WP_234639636.1
Coordinates 110431..110853 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag L1Z78_RS00500 Protein ID WP_234639637.1
Coordinates 110840..111073 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1Z78_RS00470 (TML_00093) 106558..107571 + 1014 WP_234639631.1 acyl-CoA dehydrogenase family protein -
L1Z78_RS00475 (TML_00094) 107584..108372 + 789 WP_234639632.1 crotonase/enoyl-CoA hydratase family protein -
L1Z78_RS00480 (TML_00095) 108528..109268 + 741 WP_234639633.1 septum site-determining protein MinC -
L1Z78_RS00485 (TML_00096) 109318..110133 + 816 WP_234639634.1 septum site-determining protein MinD -
L1Z78_RS00490 (TML_00097) 110140..110403 + 264 WP_234639635.1 cell division topological specificity factor MinE -
L1Z78_RS00495 (TML_00098) 110431..110853 - 423 WP_234639636.1 PIN domain-containing protein Toxin
L1Z78_RS00500 (TML_00099) 110840..111073 - 234 WP_234639637.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
L1Z78_RS00505 (TML_00100) 111152..111673 - 522 WP_234639638.1 flavin reductase family protein -
L1Z78_RS00510 (TML_00101) 111820..112455 - 636 WP_234639639.1 3'-5' exonuclease -
L1Z78_RS00515 (TML_00102) 112500..112988 - 489 WP_234639640.1 homoprotocatechuate degradation operon regulator HpaR -
L1Z78_RS00520 (TML_00103) 113063..113884 - 822 WP_234639641.1 aldolase/citrate lyase family protein -
L1Z78_RS00525 (TML_00104) 113902..115356 - 1455 WP_234639642.1 NAD-dependent succinate-semialdehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(12-122)

Antitoxin

SpoVT-AbrB domain

(5-37)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15013.23 Da        Isoelectric Point: 5.9613

>T289375 WP_234639636.1 NZ_LR813084:c110853-110431 [Delftia tsuruhatensis]
MQEIEARAGASFLDSNVVLYLLSAESAKAGSAEALLKTGPVISVQVLNEVTHVCIRKLHMGWNDVEQFLALVRSFCRVVP
LTEDIHDLARQIAPRNGLSFYDACIVAAATASGCTTLHSEDMNHGQAIGSLTLCNPFKAA

Download         Length: 423 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8629.68 Da        Isoelectric Point: 6.3430

>AT289375 WP_234639637.1 NZ_LR813084:c111073-110840 [Delftia tsuruhatensis]
MQVSKWGNSLAVRLPAAVVQALELREGDDIEITVEGSRSFAVRKAPSDEERLESLRAFRGRLPAGFRFNRDEANARD

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References