Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2519933..2520518 Replicon chromosome
Accession NZ_LR796240
Organism Treponema socranskii subsp. buccale strain Marseille-CSURQ0203

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H1X50_RS11435 Protein ID WP_180487323.1
Coordinates 2520210..2520518 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID U1F7W0
Locus tag H1X50_RS11430 Protein ID WP_021330949.1
Coordinates 2519933..2520226 (-) Length 98 a.a.

Genomic Context

H1X50_RS11420H1X50_RS11425H1X50_RS11415H1X50_RS11430H1X50_RS11435H1X50_RS11440H1X50_RS11445H1X50_RS11450H1X50_RS11455H1X50_RS11460H1X50_RS11465
Location: 2517092..2519482 (2391 bp)
Type: Others
Protein ID: WP_180487322.1
Location: 2519625..2519912 (288 bp)
Type: Others
Protein ID: WP_197927145.1
Location: 2515344..2516546 (1203 bp)
Type: Others
Protein ID: WP_180487321.1
Location: 2519933..2520226 (294 bp)
Type: Antitoxin
Protein ID: WP_021330949.1
Location: 2520210..2520518 (309 bp)
Type: Toxin
Protein ID: WP_180487323.1
Location: 2520683..2520976 (294 bp)
Type: Others
Protein ID: WP_180487324.1
Location: 2520978..2521289 (312 bp)
Type: Others
Protein ID: WP_197927116.1
Location: 2521437..2521850 (414 bp)
Type: Others
Protein ID: WP_180487326.1
Location: 2521913..2524270 (2358 bp)
Type: Others
Protein ID: WP_180487327.1
Location: 2524242..2524871 (630 bp)
Type: Others
Protein ID: WP_180487328.1
Location: 2524904..2525329 (426 bp)
Type: Others
Protein ID: WP_180487329.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
H1X50_RS114152515344..2516546-1203WP_180487321.1dicarboxylate/amino acid:cation symporter-
H1X50_RS114202517092..2519482+2391WP_180487322.1MMPL family transporter-
H1X50_RS114252519625..2519912+288WP_197927145.1HigA family addiction module antidote protein-
H1X50_RS114302519933..2520226-294WP_021330949.1putative addiction module antidote proteinAntitoxin
H1X50_RS114352520210..2520518-309WP_180487323.1type II toxin-antitoxin system RelE/ParE family toxinToxin
H1X50_RS114402520683..2520976-294WP_180487324.1putative addiction module antidote protein-
H1X50_RS114452520978..2521289-312WP_197927116.1type II toxin-antitoxin system RelE/ParE family toxin-
H1X50_RS114502521437..2521850-414WP_180487326.1hypothetical protein-
H1X50_RS114552521913..2524270-2358WP_180487327.1MMPL family transporter-
H1X50_RS114602524242..2524871-630WP_180487328.1outer membrane lipoprotein carrier protein LolA-
H1X50_RS114652524904..2525329-426WP_180487329.1acyl-CoA thioesterase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-91)

Antitoxin

Uncharacterized protein HI1420

(3-92)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11441.22 Da        Isoelectric Point: 10.3602

>T289373 WP_180487323.1 NZ_LR796240:c2520518-2520210 [Treponema socranskii subsp. buccale]
VYKVLQTETYKKWFKKLRDERAKFAIGQRIARMTVGNFGDSKTVGGGVFELRIDVGKGYRVYFTNNGKQIVILLVGGDKS
TQDEDIKTAKKMAGGIDYGKID

Download         Length: 309 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10699.22 Da        Isoelectric Point: 4.8228

>AT289373 WP_021330949.1 NZ_LR796240:c2520226-2519933 [Treponema socranskii subsp. buccale]
MEKLTEFDMAEYLDTEELQKGYLDYNAKEGTPEDLLRAINAVARARGMTKTAKEAGITRDGLYKALAPEANPAFSTVFNI
LHAIGYTLTPTPIAKTM

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBU1F7W0

References