Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 3184402..3185093 Replicon chromosome
Accession NZ_LR792684
Organism Kyrpidia spormannii isolate FAVT5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HKD36_RS15540 Protein ID WP_170099945.1
Coordinates 3184656..3185093 (+) Length 146 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HKD36_RS15535 Protein ID WP_170099944.1
Coordinates 3184402..3184659 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKD36_RS15500 3180383..3180808 - 426 WP_170099940.1 putative toxin-antitoxin system toxin component, PIN family -
HKD36_RS15505 3180805..3181050 - 246 WP_170099941.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
HKD36_RS15510 3181131..3181368 + 238 Protein_3036 type II toxin-antitoxin system Phd/YefM family antitoxin -
HKD36_RS15515 3181365..3181514 + 150 Protein_3037 PIN domain-containing protein -
HKD36_RS15520 3181596..3182138 - 543 WP_170099942.1 ImmA/IrrE family metallo-endopeptidase -
HKD36_RS15525 3182305..3183644 - 1340 Protein_3039 transposase -
HKD36_RS15530 3183797..3184174 - 378 WP_170099943.1 hypothetical protein -
HKD36_RS15535 3184402..3184659 + 258 WP_170099944.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HKD36_RS15540 3184656..3185093 + 438 WP_170099945.1 type II toxin-antitoxin system VapC family toxin Toxin
HKD36_RS15545 3186088..3186612 - 525 WP_170099946.1 Uma2 family endonuclease -
HKD36_RS15550 3186643..3186852 - 210 WP_197945651.1 hypothetical protein -
HKD36_RS15555 3186955..3187290 - 336 WP_170086642.1 hypothetical protein -
HKD36_RS15560 3187283..3187849 - 567 WP_170086771.1 IS630 family transposase -
HKD36_RS15565 3187797..3188342 - 546 WP_170099947.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(5-66)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 16405.82 Da        Isoelectric Point: 7.1376

>T289371 WP_170099945.1 NZ_LR792684:3184656-3185093 [Kyrpidia spormannii]
VKYLLDTCVISELVKRAPAPAVLRWVENQDEENLYLSVLTLGELQRGVSKLLDRSRAEQLQAWLNDDLTHRFQRRILPVD
QKVAKAWGEISGDAARRGETLPVMDSLIAATAQVHGLVVVTRNVRDIERCRVPVTNPWPDTRADL

Download         Length: 438 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9741.34 Da        Isoelectric Point: 10.3461

>AT289371 WP_170099944.1 NZ_LR792684:3184402-3184659 [Kyrpidia spormannii]
MVMDKTWQLQDAKNRLSELVHKAMRNGPQMITVRGKPAVVVVSVQEYERLVRPKTSLVEFFRSSPLVGVELDAERLRDHP
REAGL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References