Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3181012..3181157 Replicon chromosome
Accession NZ_LR792628
Organism Klebsiella pneumoniae isolate SB5881

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3181019..3181121 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3181012..3181157 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HU711_RS15540 3176544..3177977 + 1434 WP_016529029.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HU711_RS15545 3178093..3178332 + 240 WP_002911393.1 YebV family protein -
HU711_RS15550 3178430..3178621 + 192 WP_002911395.1 YebW family protein -
HU711_RS15555 3178618..3179271 - 654 WP_016529030.1 protein-serine/threonine phosphatase -
HU711_RS15560 3179428..3180396 + 969 WP_004151446.1 VirK/YbjX family protein -
HU711_RS15565 3180501..3180644 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3181012..3181157 + 146 - - Antitoxin
- 3181019..3181121 - 103 - - Toxin
HU711_RS15570 3181280..3181618 - 339 WP_016529031.1 YebY family protein -
HU711_RS15575 3181635..3182504 - 870 WP_004184661.1 copper homeostasis membrane protein CopD -
HU711_RS15580 3182508..3182882 - 375 WP_016529032.1 CopC domain-containing protein YobA -
HU711_RS15585 3182995..3183225 + 231 WP_002911406.1 DNA polymerase III subunit theta -
HU711_RS15590 3183304..3183963 + 660 WP_002911407.1 exodeoxyribonuclease X -
HU711_RS15595 3183967..3186027 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T289354 NZ_LR792628:c3181121-3181019 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT289354 NZ_LR792628:3181012-3181157 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References