Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 437794..438457 Replicon chromosome
Accession NC_020260
Organism Cronobacter sakazakii SP291

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag CSSP291_RS02210 Protein ID WP_004385675.1
Coordinates 438041..438457 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag CSSP291_RS02205 Protein ID WP_004385674.1
Coordinates 437794..438060 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSSP291_RS02180 432823..434256 - 1434 WP_004385669.1 6-phospho-beta-glucosidase -
CSSP291_RS02185 434408..435136 - 729 WP_004385670.1 MurR/RpiR family transcriptional regulator -
CSSP291_RS02190 435313..435627 + 315 WP_004385671.1 N(4)-acetylcytidine aminohydrolase -
CSSP291_RS02195 435769..436422 + 654 WP_004385672.1 hemolysin III family protein -
CSSP291_RS02200 436527..437516 - 990 WP_004385673.1 tRNA-modifying protein YgfZ -
CSSP291_RS02205 437794..438060 + 267 WP_004385674.1 FAD assembly factor SdhE Antitoxin
CSSP291_RS02210 438041..438457 + 417 WP_004385675.1 protein YgfX Toxin
CSSP291_RS02215 438471..438992 - 522 WP_004385676.1 flavodoxin FldB -
CSSP291_RS02220 439094..439990 + 897 WP_004385677.1 site-specific tyrosine recombinase XerD -
CSSP291_RS02225 440013..440732 + 720 WP_004385678.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
CSSP291_RS02230 440736..442469 + 1734 WP_004385679.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16446.46 Da        Isoelectric Point: 11.4887

>T28935 WP_004385675.1 NC_020260:438041-438457 [Cronobacter sakazakii SP291]
VVLWHSDLRVSWRSQWLSLLLHGAVAVIILLLPWPLRYLPVWMLLLSLVVFDCVRSQRRINAFQGEVSLTADYQLRWQGV
DWQICATPWMLRSGMMLRLRHPKTTRRHHVWLAADSMTEAEWRDLRRLLLQQPIGDKR

Download         Length: 417 bp

>T28935 NC_020260:438041-438457 [Cronobacter sakazakii SP291]
GTGGTCCTGTGGCACTCTGATCTTCGCGTTTCATGGCGCTCGCAGTGGCTATCGCTGCTGCTGCACGGCGCCGTGGCCGT
TATTATTTTGCTGCTCCCCTGGCCGCTGCGGTATCTGCCCGTGTGGATGCTGTTGCTGTCTCTGGTGGTGTTTGACTGCG
TGCGTAGCCAACGGCGTATCAATGCGTTTCAGGGCGAGGTCAGCCTGACGGCTGATTATCAGCTACGCTGGCAGGGCGTT
GACTGGCAGATTTGCGCCACGCCCTGGATGTTGCGCAGCGGAATGATGCTGCGGCTGCGTCATCCGAAAACGACGCGCCG
CCATCATGTCTGGCTGGCGGCGGATAGCATGACGGAAGCGGAGTGGCGCGATTTGCGTCGCCTTCTGTTGCAACAGCCCA
TAGGCGACAAACGCTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10358.84 Da        Isoelectric Point: 4.6289

>AT28935 WP_004385674.1 NC_020260:437794-438060 [Cronobacter sakazakii SP291]
MDINNKARIHWACRRGMRELDISIMPFFEYDYDSLSDEDKCVFVRLLECDDPDLFNWLMNHGKPADAELARMVELIQQRN
QARGPVAL

Download         Length: 267 bp

>AT28935 NC_020260:437794-438060 [Cronobacter sakazakii SP291]
ATGGATATTAATAATAAAGCCCGTATTCATTGGGCATGTCGCAGAGGTATGCGCGAGCTGGATATTTCCATCATGCCTTT
CTTTGAATATGACTATGACTCCCTGAGCGACGAAGACAAATGCGTTTTTGTCCGCCTGCTGGAGTGTGACGATCCTGATT
TATTCAACTGGCTGATGAATCACGGCAAGCCAGCTGATGCGGAGCTGGCGCGAATGGTGGAATTAATCCAGCAGCGGAAT
CAGGCACGTGGTCCTGTGGCACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References