Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2295273..2295544 Replicon chromosome
Accession NZ_LR782232
Organism Escherichia coli isolate SC467

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2295403..2295506 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2295273..2295544 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV361_RS10885 2291828..2292490 - 663 WP_000944256.1 exodeoxyribonuclease X -
HV361_RS10890 2292514..2293170 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
HV361_RS10895 2293272..2293502 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HV361_RS10900 2293641..2294015 + 375 WP_000204699.1 CopC domain-containing protein YobA -
HV361_RS10905 2294019..2294891 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
HV361_RS10910 2294904..2295245 + 342 WP_000976492.1 YebY family protein -
- 2295273..2295544 - 272 - - Antitoxin
- 2295403..2295506 + 104 - - Toxin
HV361_RS10915 2295641..2296297 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
HV361_RS10920 2296298..2296489 - 192 WP_001296140.1 YebW family protein -
HV361_RS10925 2296594..2296830 - 237 WP_001295499.1 DUF1480 family protein -
HV361_RS10930 2296948..2298387 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T289336 NZ_LR782232:2295403-2295506 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT289336 NZ_LR782232:c2295544-2295273 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References