Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 60579..61113 Replicon plasmid pI
Accession NZ_LR778302
Organism Denitratisoma oestradiolicum strain DSM 16959

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DENOEST_RS19460 Protein ID WP_183148372.1
Coordinates 60579..60860 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DENOEST_RS19465 Protein ID WP_183148373.1
Coordinates 60847..61113 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DENOEST_RS19440 55820..56038 + 219 WP_183148368.1 hypothetical protein -
DENOEST_RS19445 56070..56858 - 789 WP_183148369.1 phage Gp37/Gp68 family protein -
DENOEST_RS19450 56858..57922 - 1065 WP_183148370.1 DNA-binding protein -
DENOEST_RS19455 59480..60445 - 966 WP_183148371.1 replication initiator protein A -
DENOEST_RS19460 60579..60860 - 282 WP_183148372.1 type II toxin-antitoxin system YafQ family toxin Toxin
DENOEST_RS19465 60847..61113 - 267 WP_183148373.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DENOEST_RS19470 61190..62830 - 1641 WP_183148374.1 hypothetical protein -
DENOEST_RS19475 62903..63277 - 375 WP_183148375.1 hypothetical protein -
DENOEST_RS19480 63359..64645 - 1287 WP_183148376.1 ParB/RepB/Spo0J family partition protein -
DENOEST_RS19485 64658..65440 - 783 WP_183148377.1 ParA family protein -
DENOEST_RS19490 65468..65887 - 420 WP_183148378.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..124849 124849


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-81)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10697.26 Da        Isoelectric Point: 9.5018

>T289328 WP_183148372.1 NZ_LR778302:c60860-60579 [Denitratisoma oestradiolicum]
MRTIDRSSAFKRDYKREAKGQHRATLDDALKPVLMALVTDQLLDARYRDHDLSGAWGGYRECHIKPDLLLIYRKLDGDVL
RLARLGSHSELFG

Download         Length: 282 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9488.88 Da        Isoelectric Point: 7.0125

>AT289328 WP_183148373.1 NZ_LR778302:c61113-60847 [Denitratisoma oestradiolicum]
MSTADTYVRARIDTNTKERAAAALDAMGLSISDAIRLLMLRVADERRLPFDVKVPNATTRKAIAELEAGKGAKFASVDAL
MADLHADN

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References