Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 4015164..4015701 Replicon chromosome
Accession NZ_LR778301
Organism Denitratisoma oestradiolicum strain DSM 16959

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag DENOEST_RS18360 Protein ID WP_145770370.1
Coordinates 4015420..4015701 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DENOEST_RS18355 Protein ID WP_145770371.1
Coordinates 4015164..4015433 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DENOEST_RS18340 4010407..4011942 - 1536 WP_145770373.1 class I SAM-dependent methyltransferase -
DENOEST_RS18345 4012113..4014758 - 2646 WP_145770372.1 calcium-binding protein -
DENOEST_RS18350 4014825..4014920 - 96 Protein_3619 hypothetical protein -
DENOEST_RS18355 4015164..4015433 + 270 WP_145770371.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
DENOEST_RS18360 4015420..4015701 + 282 WP_145770370.1 type II toxin-antitoxin system YafQ family toxin Toxin
DENOEST_RS18365 4015818..4017020 - 1203 WP_145770369.1 site-specific integrase -
DENOEST_RS18370 4017850..4018653 + 804 WP_145770368.1 hypothetical protein -
DENOEST_RS18375 4018975..4019895 - 921 WP_145770367.1 replication protein C -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-85)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10663.19 Da        Isoelectric Point: 9.5732

>T289326 WP_145770370.1 NZ_LR778301:4015420-4015701 [Denitratisoma oestradiolicum]
MRTIERSSAFKRDYKRESKGAHRASLDTDLVHVLTALVHDKPLPAKLRDHDLSGDWAGYRECHIKPDLLLIYRKPDAETL
RLARLGSHSELFG

Download         Length: 282 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9772.23 Da        Isoelectric Point: 7.2046

>AT289326 WP_145770371.1 NZ_LR778301:4015164-4015433 [Denitratisoma oestradiolicum]
MNTAADTYVRARIDSATKERAATALEAMGLSISDAIRLLMLRVADERRLPFEVKAPNTVTRKAMAELEAGKGKRFASVED
LMADLHAHD

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References