Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-YefM
Location 2905252..2905754 Replicon chromosome
Accession NZ_LR778301
Organism Denitratisoma oestradiolicum strain DSM 16959

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag DENOEST_RS13095 Protein ID WP_145772142.1
Coordinates 2905252..2905506 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag DENOEST_RS13100 Protein ID WP_145772143.1
Coordinates 2905503..2905754 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DENOEST_RS13080 2900802..2901710 + 909 WP_145772045.1 helix-turn-helix domain-containing protein -
DENOEST_RS13085 2901771..2903060 - 1290 WP_197970617.1 group II intron reverse transcriptase/maturase -
DENOEST_RS13090 2904538..2905164 + 627 WP_145772141.1 hypothetical protein -
DENOEST_RS13095 2905252..2905506 - 255 WP_145772142.1 Txe/YoeB family addiction module toxin Toxin
DENOEST_RS13100 2905503..2905754 - 252 WP_145772143.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DENOEST_RS13105 2906053..2907021 - 969 Protein_2593 IS110 family transposase -
DENOEST_RS13110 2907069..2907548 + 480 WP_145772144.1 tyrosine-type recombinase/integrase -
DENOEST_RS13120 2907829..2909193 + 1365 WP_145772145.1 hypothetical protein -
DENOEST_RS13125 2909186..2910496 - 1311 WP_145772146.1 adenylosuccinate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10321.82 Da        Isoelectric Point: 8.4859

>T289325 WP_145772142.1 NZ_LR778301:c2905506-2905252 [Denitratisoma oestradiolicum]
VKLIFSDEAWEDYLYWQKQDKRMVERINKLIRETEREPFNGVGKPEPLKHALSGFWSRRITDEHRMVYRVVNDALEIVQL
RFHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9105.52 Da        Isoelectric Point: 8.0081

>AT289325 WP_145772143.1 NZ_LR778301:c2905754-2905503 [Denitratisoma oestradiolicum]
MDAITYTTARANLATTMDRVCNDHEALIITRNGEQAVVMLSLEDFKALEETAYLLRTPANAKRLLSAIAQLNAGKGVERK
LAK

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References