Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 141074..141634 Replicon chromosome
Accession NZ_LR778174
Organism Veillonella parvula strain SKV38

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FNLLGLLA_RS00420 Protein ID WP_021147561.1
Coordinates 141074..141346 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID T0TA56
Locus tag FNLLGLLA_RS00425 Protein ID WP_004697933.1
Coordinates 141353..141634 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FNLLGLLA_RS00390 136095..137618 + 1524 WP_004697952.1 ABC transporter substrate-binding protein -
FNLLGLLA_RS00395 137611..138378 + 768 WP_118091133.1 ABC transporter ATP-binding protein -
FNLLGLLA_RS00400 138380..139120 + 741 WP_118091132.1 dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein -
FNLLGLLA_RS00405 139325..139552 + 228 WP_042986318.1 hypothetical protein -
FNLLGLLA_RS00410 139518..140411 + 894 WP_021147559.1 hypothetical protein -
FNLLGLLA_RS00415 140498..140845 - 348 WP_174892135.1 hypothetical protein -
FNLLGLLA_RS00420 141074..141346 - 273 WP_021147561.1 type II toxin-antitoxin system YafQ family toxin Toxin
FNLLGLLA_RS00425 141353..141634 - 282 WP_004697933.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FNLLGLLA_RS00430 141827..142456 + 630 WP_118091131.1 hypothetical protein -
FNLLGLLA_RS00435 142573..142977 + 405 WP_021147563.1 hypothetical protein -
FNLLGLLA_RS00440 143111..143626 - 516 WP_021147564.1 DUF308 domain-containing protein -
FNLLGLLA_RS00445 144141..145679 + 1539 WP_077708644.1 2-isopropylmalate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-69)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10550.31 Da        Isoelectric Point: 10.1258

>T289321 WP_021147561.1 NZ_LR778174:c141346-141074 [Veillonella parvula]
MLRLVLSSKFKKDLKRSKKRGKDLNKLYSIITKLQNQTLLDPSYKDHPLTGNYEGFRELHIEPDWLLIYAIKDDMLVLSL
TRTGSHSDLF

Download         Length: 273 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10159.70 Da        Isoelectric Point: 5.0931

>AT289321 WP_004697933.1 NZ_LR778174:c141634-141353 [Veillonella parvula]
MAKTASISLRIEPAVKAQLEALYASFGISVTDAINIFLHTSLMEGGFPFQPKQPRYNAETEAAIQETKDILAGKVKAKSY
ANVKEMIEDLGLE

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2S7Z1D3

References