Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 141074..141634 Replicon chromosome
Accession NZ_LR778174
Organism Veillonella parvula strain SKV38

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FNLLGLLA_RS00420 Protein ID WP_021147561.1
Coordinates 141074..141346 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID T0TA56
Locus tag FNLLGLLA_RS00425 Protein ID WP_004697933.1
Coordinates 141353..141634 (-) Length 94 a.a.

Genomic Context

FNLLGLLA_RS00390FNLLGLLA_RS00395FNLLGLLA_RS00400FNLLGLLA_RS00405FNLLGLLA_RS00410FNLLGLLA_RS00430FNLLGLLA_RS00435FNLLGLLA_RS00445FNLLGLLA_RS00415FNLLGLLA_RS00420FNLLGLLA_RS00425FNLLGLLA_RS00440
Location: 136095..137618 (1524 bp)
Type: Others
Protein ID: WP_004697952.1
Location: 137611..138378 (768 bp)
Type: Others
Protein ID: WP_118091133.1
Location: 138380..139120 (741 bp)
Type: Others
Protein ID: WP_118091132.1
Location: 139325..139552 (228 bp)
Type: Others
Protein ID: WP_042986318.1
Location: 139518..140411 (894 bp)
Type: Others
Protein ID: WP_021147559.1
Location: 141827..142456 (630 bp)
Type: Others
Protein ID: WP_118091131.1
Location: 142573..142977 (405 bp)
Type: Others
Protein ID: WP_021147563.1
Location: 144141..145679 (1539 bp)
Type: Others
Protein ID: WP_077708644.1
Location: 140498..140845 (348 bp)
Type: Others
Protein ID: WP_174892135.1
Location: 141074..141346 (273 bp)
Type: Toxin
Protein ID: WP_021147561.1
Location: 141353..141634 (282 bp)
Type: Antitoxin
Protein ID: WP_004697933.1
Location: 143111..143626 (516 bp)
Type: Others
Protein ID: WP_021147564.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FNLLGLLA_RS00390136095..137618+1524WP_004697952.1ABC transporter substrate-binding protein-
FNLLGLLA_RS00395137611..138378+768WP_118091133.1ABC transporter ATP-binding protein-
FNLLGLLA_RS00400138380..139120+741WP_118091132.1dipeptide/oligopeptide/nickel ABC transporter ATP-binding protein-
FNLLGLLA_RS00405139325..139552+228WP_042986318.1hypothetical protein-
FNLLGLLA_RS00410139518..140411+894WP_021147559.1hypothetical protein-
FNLLGLLA_RS00415140498..140845-348WP_174892135.1hypothetical protein-
FNLLGLLA_RS00420141074..141346-273WP_021147561.1type II toxin-antitoxin system YafQ family toxinToxin
FNLLGLLA_RS00425141353..141634-282WP_004697933.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
FNLLGLLA_RS00430141827..142456+630WP_118091131.1hypothetical protein-
FNLLGLLA_RS00435142573..142977+405WP_021147563.1hypothetical protein-
FNLLGLLA_RS00440143111..143626-516WP_021147564.1DUF308 domain-containing protein-
FNLLGLLA_RS00445144141..145679+1539WP_077708644.12-isopropylmalate synthase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-69)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10550.31 Da        Isoelectric Point: 10.1258

>T289321 WP_021147561.1 NZ_LR778174:c141346-141074 [Veillonella parvula]
MLRLVLSSKFKKDLKRSKKRGKDLNKLYSIITKLQNQTLLDPSYKDHPLTGNYEGFRELHIEPDWLLIYAIKDDMLVLSL
TRTGSHSDLF

Download         Length: 273 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10159.70 Da        Isoelectric Point: 5.0931

>AT289321 WP_004697933.1 NZ_LR778174:c141634-141353 [Veillonella parvula]
MAKTASISLRIEPAVKAQLEALYASFGISVTDAINIFLHTSLMEGGFPFQPKQPRYNAETEAAIQETKDILAGKVKAKSY
ANVKEMIEDLGLE

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A2S7Z1D3

References