Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 289875..290146 Replicon chromosome
Accession NZ_LR778149
Organism Escherichia coli isolate SC487

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 290005..290108 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 289875..290146 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H1C96_RS01460 286430..287092 - 663 WP_000944256.1 exodeoxyribonuclease X -
H1C96_RS01465 287116..287772 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H1C96_RS01470 287874..288104 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H1C96_RS01475 288243..288617 + 375 WP_000204700.1 CopC domain-containing protein YobA -
H1C96_RS01480 288621..289493 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
H1C96_RS01485 289506..289847 + 342 WP_000976472.1 YebY family protein -
- 289875..290146 - 272 - - Antitoxin
- 290005..290108 + 104 - - Toxin
H1C96_RS01490 290243..290899 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
H1C96_RS01495 290900..291091 - 192 WP_001296140.1 YebW family protein -
H1C96_RS01500 291196..291432 - 237 WP_001295499.1 DUF1480 family protein -
H1C96_RS01505 291550..292989 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T289228 NZ_LR778149:290005-290108 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT289228 NZ_LR778149:c290146-289875 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References