Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2321973..2322244 Replicon chromosome
Accession NZ_LR778145
Organism Escherichia coli isolate SC423

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2322103..2322206 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2321973..2322244 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H1C75_RS11005 2318528..2319190 - 663 WP_000944256.1 exodeoxyribonuclease X -
H1C75_RS11010 2319214..2319870 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H1C75_RS11015 2319972..2320202 - 231 WP_000916759.1 DNA polymerase III subunit theta -
H1C75_RS11020 2320341..2320715 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H1C75_RS11025 2320719..2321591 + 873 WP_160385102.1 copper homeostasis membrane protein CopD -
H1C75_RS11030 2321604..2321945 + 342 WP_000976472.1 YebY family protein -
- 2321973..2322244 - 272 - - Antitoxin
- 2322103..2322206 + 104 - - Toxin
H1C75_RS11035 2322341..2322997 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
H1C75_RS11040 2322998..2323189 - 192 WP_001296140.1 YebW family protein -
H1C75_RS11045 2323294..2323530 - 237 WP_001295499.1 DUF1480 family protein -
H1C75_RS11050 2323648..2325087 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T289158 NZ_LR778145:2322103-2322206 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT289158 NZ_LR778145:c2322244-2321973 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References