Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2283652..2283920 Replicon chromosome
Accession NZ_LR778142
Organism Escherichia coli isolate SC434

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2283690..2283792 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2283652..2283920 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H1D10_RS11245 2280809..2282248 + 1440 WP_097420077.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
H1D10_RS11250 2282366..2282602 + 237 WP_001295499.1 DUF1480 family protein -
H1D10_RS11255 2282707..2282898 + 192 WP_001317886.1 YebW family protein -
H1D10_RS11260 2282899..2283555 - 657 WP_001357783.1 protein-serine/threonine phosphatase -
- 2283652..2283920 + 269 - - Antitoxin
- 2283690..2283792 - 103 - - Toxin
H1D10_RS11265 2283950..2284291 - 342 WP_000976472.1 YebY family protein -
H1D10_RS11270 2284304..2285176 - 873 WP_112886263.1 copper homeostasis membrane protein CopD -
H1D10_RS11275 2285180..2285554 - 375 WP_000168747.1 CopC domain-containing protein YobA -
H1D10_RS11280 2285693..2285923 + 231 WP_000916763.1 DNA polymerase III subunit theta -
H1D10_RS11285 2286025..2286681 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
H1D10_RS11290 2286705..2287367 + 663 WP_000944249.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T289117 NZ_LR778142:c2283792-2283690 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT289117 NZ_LR778142:2283652-2283920 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References