Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) paaR-paaA-parE/-
Location 806227..806705 Replicon chromosome
Accession NZ_LR778141
Organism Escherichia coli isolate SC407

Toxin (Protein)


Gene name parE_1 Uniprot ID A0A7D8WGY6
Locus tag H1C92_RS04005 Protein ID WP_000936798.1
Coordinates 806227..806514 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name paaA Uniprot ID A0A7D8X397
Locus tag H1C92_RS04010 Protein ID WP_024207685.1
Coordinates 806514..806705 (-) Length 64 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 796405..848579 52174


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-91)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 96 a.a.        Molecular weight: 10899.83 Da        Isoelectric Point: 10.1360

>T289088 WP_000936798.1 NZ_LR778141:c806514-806227 [Escherichia coli]
MLPILWLPSARDDLRQIVAYIAKENIPAARRLKIRIETSVLALSEHPYLYPPSDRVSGLREIVVHPNYIVLYRVAASSIE
IANIVHARRQFPFPI

Download         Length: 288 bp


Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7017.77 Da        Isoelectric Point: 4.0270

>AT289088 WP_024207685.1 NZ_LR778141:c806705-806514 [Escherichia coli]
MSTALSPIVSEFETTEQENSYNEWLRAKVASSLADPRPSIPHDEVMAEIENLIAQIAVTNRSE

Download         Length: 192 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A7D8WGY6


Antitoxin

Source ID Structure
AlphaFold DB A0A7D8X397

References