Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2136244..2136515 Replicon chromosome
Accession NZ_LR778140
Organism Escherichia coli isolate SC406

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2136374..2136477 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2136244..2136515 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H1C94_RS10080 2132799..2133461 - 663 WP_000944256.1 exodeoxyribonuclease X -
H1C94_RS10085 2133485..2134141 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
H1C94_RS10090 2134243..2134473 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H1C94_RS10095 2134612..2134986 + 375 WP_000204699.1 CopC domain-containing protein YobA -
H1C94_RS10100 2134990..2135862 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
H1C94_RS10105 2135875..2136216 + 342 WP_000976492.1 YebY family protein -
- 2136244..2136515 - 272 - - Antitoxin
- 2136374..2136477 + 104 - - Toxin
H1C94_RS10110 2136612..2137268 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
H1C94_RS10115 2137269..2137460 - 192 WP_001296140.1 YebW family protein -
H1C94_RS10120 2137565..2137801 - 237 WP_001295499.1 DUF1480 family protein -
H1C94_RS10125 2137919..2139358 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T289069 NZ_LR778140:2136374-2136477 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT289069 NZ_LR778140:c2136515-2136244 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCTTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References