289057

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemK-mazE/MazF(toxin)
Location 1475138..1475763 Replicon chromosome
Accession NZ_LR746496
Organism Acididesulfobacillus acetoxydans isolate PacBioINE

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag MNU25_RS06530 Protein ID WP_045574608.1
Coordinates 1475413..1475763 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag MNU25_RS06525 Protein ID WP_240984334.1
Coordinates 1475138..1475413 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNU25_RS06505 (DEACI_1344) 1470868..1471608 + 741 WP_240984330.1 hypothetical protein -
MNU25_RS06510 (DEACI_1345) 1471670..1471921 + 252 WP_240984331.1 hypothetical protein -
MNU25_RS06515 (DEACI_1346) 1472317..1473765 + 1449 WP_240984332.1 Mur ligase family protein -
MNU25_RS06520 (DEACI_1347) 1473762..1474667 + 906 WP_240984333.1 glutamine amidotransferase -
MNU25_RS06525 (DEACI_1348) 1475138..1475413 + 276 WP_240984334.1 ribbon-helix-helix protein, CopG family Antitoxin
MNU25_RS06530 (DEACI_1349) 1475413..1475763 + 351 WP_045574608.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
MNU25_RS06535 (DEACI_1350) 1476043..1476465 + 423 WP_240984335.1 PaaI family thioesterase -
MNU25_RS06540 (DEACI_1351) 1476577..1477296 + 720 WP_240984336.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
MNU25_RS06545 (DEACI_1354) 1478021..1479322 + 1302 WP_240984337.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-39)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12794.84 Da        Isoelectric Point: 5.8944

>T289057 WP_045574608.1 NZ_LR746496:1475413-1475763 [Acididesulfobacillus acetoxydans]
MIIKRGEIYYAELNPVVGSEQGGTRPVLVIQNDIGNQFSPTTIIAAITSQIAKAKLPTHVEVRAKRSGLERDSVILTEQI
RTIDKSRLKEKVAVLDEEVMLRVDQAIEISLGLADI

Download         Length: 351 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10704.26 Da        Isoelectric Point: 5.9306

>AT289057 WP_240984334.1 NZ_LR746496:1475138-1475413 [Acididesulfobacillus acetoxydans]
VAESKRIMISLPESLLAEVDGIVTLEKRNRSEFIREAINSVLHERRRRGIREQMRRGYQEMAQLNLAIAKELFSTEQEAL
EDFERTIVECR

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References